Bone marrow stem cells participate in tissue repair processes and may have roles in skin wound repair. Diabetes is characterized by delayed and poor wound healing, and type 1 diabetes seems to lead to stem cell dysfunction. Hence, stem cell dysfunction could contribute to poor healing, and stem cell-based therapies may be efficacious in diabetic wounds. We investigated the potential of exogenou...

Aim. To evaluate the effects of autologous blood vessels and nerves on vascularization. Methods. A dog model of tissue-engineered bone vascularization was established by constructing inferior alveolar neurovascular bundles through the mandibular canal. Sixteen 12-month-old healthy beagles were randomly divided into two groups (n=8). Group A retained inferior alveolar neurovascular bundles, and ...

(i) What are the chief lesions associated with vascularization of the cornea ? (ii) To what extent do the various modes of vascularization facilitate a differentia! diagnosis ? (iii) Is there a demonstrable factor common to the lesions concerned ? (iv) What is the real significance of these adventitious vessels ? (v) Does experimental work throw any light upon the problem ? (vi) Is it possible ...

Homozygous mice with a null mutation in the MMP-9/gelatinase B gene exhibit an abnormal pattern of skeletal growth plate vascularization and ossification. Although hypertrophic chondrocytes develop normally, apoptosis, vascularization, and ossification are delayed, resulting in progressive lengthening of the growth plate to about eight times normal. After 3 weeks postnatal, aberrant apoptosis, ...

A 65-year-old male presented to us with symptoms of severe pain in right eye with loss of vision for 1 week. He had undergone a manual small incision cataract surgery elsewhere 2 weeks back. 48–72 hours post-surgery, his vision started decreasing and he presented to us in a state shown in the figure 1. On examination, a provisional diagnosis of post-operative endophthalmitis was made. The anter...