BACKGROUND/OBJECTIVE Identifying which patients with varicose veins are at risk of progressing to more severe forms of chronic venous disease could help in assigning clinical priorities and targeting appropriate treatments. The aim of this study was to determine, in subjects with varicose veins, the characteristics of venous disease and other factors associated with an increased risk of ulcerat...

In our varicose vein center, on a trial basis, among the patients with asymptomatic calf deep vein thrombosis (CDVT) we carefully selected the patients for varicose vein surgery using the requirements as follows; 1) the patients had varicose veins with incompetent saphenous veins, 2) sequential examination including DUS confirmed stability and clinical insignificance of asymptomatic CDVT, 3) th...

Suprapubic varicose veins are usually indicative of unilateral iliac vein occlusion and venous collateralisation. We report two cases of suprapubic varicose veins following pelvic vein embolisation and subsequent pregnancy; both presented without residual pelvic venous reflux or pelvic venous obstruction. In both cases, there was no significant flow in the suprapubic veins indicating that they ...

Chronic venous disease is the most common vascular condition to affect the lower limb. It covers a wide range of conditions which can be broadly categorised as varicose veins, chronic venous insufficiency and venous ulcers. Venous disease is associated with a large burden of ill-health and it consumes a substantial amount of NHS resources. In the UK each year roughly half a million people consu...

BACKGROUND The results of surgery for small saphenous varicose vein (SSV) varicosities may be suboptimal in terms of recurrence and complications. The role of minimally invasive alternatives remains incompletely defined. The aim was to review the medium-term outcomes of ultrasound-guided foam sclerotherapy (UGFS) for SSV. METHODS Eighty-six patients (92 legs) undergoing UGFS for SSV were asse...

Among the suspected reasons for varicose vein formation are changes in the quantity and content of the elastin protein; however, comprehensive investigations about elastin assembly in varicose vein formation are yet lacking. In this study, we aimed to determine the changes in mRNA levels of elastin and some of its functionally related proteins, fibulin 5, LOXL-1, MMP-2 and MMP-9 in varicose vei...

V ar ic os e V ei ns Endovenous interventions have transformed the treatment of varicose veins during the past decade. Interest in minimally invasive endovenous thermal ablation of the saphenous vein has substantially increased due to multiple reasons. Both radiofrequency ablation (RFA) and endovenous laser therapy (EVLT) can be performed as an office procedure; they are less invasive and usual...

BACKGROUND The relationship between the degree of expression of matrix metalloproteinases or tissue inhibitor of metalloproteinases and venous reflux remains to be investigated. MATERIALS AND METHODS Primary varicose vein tissues were obtained from 23 patients, 18 females and 5 males, aged from 19 to 73. Cephalic or basilic veins were obtained for the control group from 10 patients who underw...