Ionic (Ii) and gating currents (Ig) from noninactivating Shaker H4 K+ channels were recorded with the cut-open oocyte voltage clamp and macropatch techniques. Steady state and kinetic properties were studied in the temperature range 2-22 degreesC. The time course of Ii elicited by large depolarizations consists of an initial delay followed by an exponential rise with two kinetic components. The...

We propose an approach to integrate the theory, simulations, and experiments in protein-folding kinetics. This is realized by measuring the mean and high-order moments of the first-passage time and its associated distribution. The full kinetics is revealed in the current theoretical framework through these measurements. In the experiments, information about the statistical properties of first-p...

in the present study, hydrilla verticillata biomass was investigated as a novel biosorbent for the uptake of basic dye malachite green from its aqueous solution. kinetic and equilibrium studies were carried out in batch process. batch adsorption experiments were conducted to study the effect of ph, temperature, sorbent dosage, initial dye concentration, and contact time for the removal malachit...

Using kinetic Monte Carlo simulations and a bond– counting ansatz, thermal stability and diffusion of an adatom island on a crystal surface are studied. At low temperatures, the diffusion constant D is found to decrease for a wide range of island sizes like D ∝ N−α, where α is close to one, N being the number of adatoms in the cluster. By heating up the surface, the system undergoes a phase tra...

this paper deals with a theoretical mathematical analysis of one-dimensional solidification problem, in which kinetic undercooling is incorporated into the this temperature condition at the interface. a model problem with nonlinear kinetic law is considered. we prove a local result intimate for the uniqueness of solution of the corresponding free boundary problem.

the objective of this research is geometrical optimization of half toroidal continuously variable transmission (cvt) in order to achieve high power transmission efficiency and low weight. after dynamic analysis of the system, the contact between the disk and the roller is modeled according to elasto-hydrodynamic lubrication principles. accordingly, a computer model is created with geometric, th...

a study of the kinetic analysis of total lead from spent car battery ash by hydrochloric acidleaching has been examined. the physico-chemical analysis of the ash powder was carried outby the inductively coupled plasma-mass spectrometry (icp-ms) and x–ray diffraction (xrd).the effects of the acid concentration, temperature and particle size on the rate of battery ashdissolution have been investi...

The muscle types present with variable fatigue tolerance, in part due to the myosin isoform expressed. However, the critical steps that define "fatigability" in vivo of fast vs. slow myosin isoforms, at the molecular level, are not yet fully understood. We examined the modulation of the ATP-induced myosin subfragment 1 (S1) dissociation from pyrene-actin by inorganic phosphate (Pi), pH, and tem...