Nanotechnology and tissue engineering have enabled engineering of nanostructured strategies to meet the current challenges in skin tissue regeneration. Electrospinning technology creates porous nanofibrous scaffolds to mimic extracellular matrix of the native tissues. The present study was performed to gain some insights into the applications of poly(l-lactic acid)-co-poly-(ε-caprolactone) (PLA...

Background During fluid challenge, volume expansion (VE)-induced increase in cardiac output (Δ VE CO) is seldom measured. Methods In patients with shock undergoing strictly controlled mechanical ventilation and receiving VE, we assessed minimally invasive surrogates for Δ VE CO (by transthoracic echocardiography): fluid-induced increases in end-tidal carbon dioxide (Δ VE E'CO2 ); pulse (Δ VE ...

Özet. Yazılım Yeniden Yapılama (software re-engineering) (YYY), yoğun kaynak ve zaman kullanımını gerektiren, gidiş-dönüşlü ve yinelemeli yazılım mühendisliği etkinliklerini içermektedir. Dolayısıyla, söz konusu süreçler otomatik hale getirilebilmeli, ortaya çıkan ürün, araç ve yöntemler yeniden yapılanmış yazılımla ilgili sonraki süreçlerde tekrar kullanılabilmelidir. Bu bağlamda, Model Güdüml...

Subject review Combining Industrial and Functional Design methodologies for the development of new products and systems requires a broad understanding of human behaviour and industrial activities. The requirements of international standards, protection of the environment and the ability to make a profit on sales requires a sound attitude and approach to succeed, especially in current economic c...

The applications of VE increase recently. Currently, the performance of VE study is mainly judged by the total amount saved by the VE team and thus ignores those issues such as team origination, VE methodology implementation, and the interactions between the facilitator and the project participants. Under these game-play rules, the VE team somehow losses its ability of identifying some shortage...

PURPOSE To evaluate the use of magnetic resonance (MR) diffusion kurtosis imaging (DKI) and dynamic contrast-enhanced MR imaging (DCE-MRI) in the differentiation of olfactory neuroblastomas (ONBs) from squamous cell carcinomas (SCCs). MATERIALS AND METHODS DKI and DCE-MRI were performed in 17 patients with ONBs and 23 patients with SCCs on a 3T MR scanner. Parameters derived from DKI and DCE-...

The regeneration of alpha-tocopherol (vitamin E; VE) by coantioxidants such as phenolics and ascorbate has been studied in homogeneous hydrocarbon solution and in biological systems. However, VE phenoxyl radicals (VE*) may be sufficiently reactive to cooxidize phenolic compounds and ascorbates. The coantioxidant behavior of some relevant phenols such as eugenol (EUG), isoeugenol (IsoEUG), 2,6-d...