نتایج جستجو برای: valerenic acid
تعداد نتایج: 747444 فیلتر نتایج به سال:
Valerian is a commonly used herbal medicinal product for the treatment of anxiety and insomnia. Here we report the stimulation of chloride currents through GABA(A) receptors (I(GABA)) by valerenic acid (VA), a constituent of Valerian. To analyse the molecular basis of VA action, we expressed GABA(A) receptors with 13 different subunit compositions in Xenopus oocytes and measured I(GABA) using t...
In this review, we have studied about Selinum vaginatum. We the essential oil which was extracted from roots of plant and also know medicinal uses S. This is found in Northwest Himalayan region including Kashmir, Kailash Parvat Himachal. particularly specific Himachal Parvati Valley Lahaul district. performed extraction using gas chromatography technique, examined through flame ionization detec...
Valerenic acid (VA)-a β2/3-selective GABA type A (GABAA) receptor modulator-displays anxiolytic and anticonvulsive effects in mice devoid of sedation, making VA an interesting drug candidate. Here we analyzed β-subunit-dependent enhancement of GABA-induced chloride currents (IGABA) by a library of VA derivatives and studied their effects on pentylenetetrazole (PTZ)-induced seizure threshold and...
The study aimed at determination of the optimum conditions for high yielding and high quality of Valeriana officinalis L. production by selecting the best variety and plantation establishment method. A higher content of active substances but lower yields of underground parts of plants were obtained in a thin-rooted variety (‘Polka’) culture, whereas an adverse tendency was observed in a thick-r...
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