BACKGROUND Borneol is the processed item from resin of Dryobalanops aromatica Gaertn. f. It can enhance the activity of antioxidant enzymes in brain tissue and reduce inflammatory response by improving the energy metabolism of ischemic brain regions, and thereby reduces brain tissue damage. The objective of this paper was to study the anti-cerebral ischemia effect of borneol and its mechanism. ...

This article discusses the role of Calcitonin Gene-Related Peptide antagonists available on market in treating cluster headaches. All treatments discussed this focus either abortive, preventive, or transitional care. These therapies include Monoclonal Antibodies (Galcanezumab, Fremanezumab, Erenumab), high-flow oxygen, triptans (sumatriptan, zolmitriptan), Octreotide, non-invasive vagus nerve s...

Objective: To carry out a 3D vector reconstruction of the nerves ventral region neck from anatomical sections “Korean Visible Human” for educational purposes. Materials and Methods: The subject was 33-year-old Korean man who died leukemia. He 164cm tall weighed 55kgs. A cryomacrotome sectioned frozen body into 5960 sections. Sections numbered 1500 to 2000 were used this study. segmentation by m...

Cerebral blood flow was measured using xenon in forty-five baboons lightly anesthetized with pentobarbital. Blood flow varied between 62 and 82 ml/lOOg/min in gray matter and between 15 and 21 ml/lOOg/min in white matter. Hypercapnia and hypoxia caused a rise in blood flow and a fall in vascular resistance. Blood flow was independent of mean arterial blood pressure over the range 60 to 130 mm H...

BACKGROUND The elucidation of the relationship between the morphology of the peripheral nerves and the diseases would be valuable in developing new medical treatments on the assumption that characteristics of the peripheral nerves in females are different from those in males. METHODS We used 13 kinds of the peripheral nerve. The materials were obtained from 10 Japanese female and male cadaver...

The baroreceptor fibers which arise from the aortic arch course centrally within the vagus nerve in the dog, and they usually follow this path in the cat. Near the origin of the superior laryngeal nerve, a separate branch of the cervical vagus (the cervical aortic nerve) arises. Previously, it was thought that this nerve contained all the important baroreceptor afferents. Aortic baroreceptor fi...

The effects of electrical stimulation of the vagus nerves have been studied in anaesthetized dogs, before and after bilateral interruption of the cardiac sympathetic nerves. During constant heart rates, maintained by right atrial pacing, vagus nerve stimulation caused small but significant reductions of myocardial contractility, but these were minor compared with the effects of other negative i...

Women diagnosed with complete spinal cord injury (SCI) at T10 or higher report sensations generated by vaginal-cervical mechanical self-stimulation (CSS). In this paper we review brain responses to sexual arousal and orgasm in such women, and further hypothesize that the afferent pathway for this unexpected perception is provided by the Vagus nerves, which bypass the spinal cord. Using function...

This study investigated whether each part of the heart is evenly innervated by the left or right vagus and observed the mechanism of compensatory recovery after unilateral cervical vagotomy. HR, BP, LVSP and +/-dp/dt max all decreased one week after left vagotomy, whereas only BP and -dp/dt max decreased one week after right vagotomy. Western blot analyses revealed that the expression of M(2) r...

Viral infection causes dysfunction of inhibitory M2 muscarinic receptors (M2Rs) on parasympathetic nerves, leading to airway hyperreactivity. The mechanisms of M2R dysfunction are incompletely understood. Double-stranded RNA (dsRNA), a product of viral replication, promotes the expression of interferons. Interferon-gamma decreases M2R gene expression in cultured airway parasympathetic neurons. ...