BACKGROUND In women with cervical cancer, treatment causes changes in vaginal anatomy and function. The effect of these changes on sexual function and the extent, if any, to which they distress women are not known. METHODS In 1996 and 1997, we attempted to contact 332 women with a history of early-stage cervical cancer (age range, 26 to 80 years) who had been treated in 1991 and 1992 at the s...

PURPOSE The purpose of this study was to examine whether or not vaginal elasticity or lack of lubrication is associated with deep or superficial dyspareunia. We investigated gynecological cancer survivors treated with radiation therapy. METHODS In a population-based study with 616 women answering a questionnaire (participation rate 78%) and who were treated with radiotherapy for gynecological...

This review attempts to assemble the characteristics of a distinct variant of sleepwalking called sexsomnia/sleepsex from the seemingly scarce literature into a coherent theoretical framework. Common features of sexsomnia include sexual arousal with autonomic activation (e.g. nocturnal erection, vaginal lubrication, nocturnal emission, dream orgasms). Somnambulistic sexual behavior and its clin...

Female sexual arousal disorders constitute a varied spectrum of difficulties, ranging from the total absence of genital or subjective pleasurable arousal to feelings of persistent genital arousal in the absence of sexual desire. Arousal disorders can be associated with physical factors (eg, vaginal dryness) or psychological factors (eg, anxiety, distraction), or a combination of both. The most ...

The menopause is understood like a menstruation cease, because of sudden fall in hormone production. Generally, the symptoms at this stage are heat waves, lack of vaginal lubrication, loss of skin elasticity, hormonal changes, intensification of bone decalcification and reduction of libido. In order to alleviate these symptoms there are Hormone Replacement Therapies (HRT) that use synthetic dru...

Objective. Many women are suffering from sexual dysfunction followed by vaginal laxity in their reproductive age. The aim of this study was to evaluate the long term effect of colpoperineoplasty on sexual function in Iranian reproductive aged women. Methods. This was a prospective observational study in which 79 women with vaginal laxity who were candidate for selective colpoperineoplasty in Ja...

Abstract Introduction Vaginal dryness is a frequent complaint, especially in post-menopausal women. The physiology underlying the production of vaginal lubrication response to arousing stimuli established; however, no current pharmacological agents successfully target mechanisms utilizing this physiology. Previous research from our lab has demonstrated that female methamphetamine (meth) users e...

OBJECTIVE We tested the effect of nonoxynol-9 (N-9) in condom lubrication on the risk of acquiring STD and genital discomfort. METHODS The study was a triple masked, randomised controlled trial comparing N-9 lubricated condoms with plain silicone lubricated condoms among Dominican female sex workers. RESULTS Randomisation provided two groups (313 for N-9 and 322 for plain) similar in baseli...

Vaginal microbicides, substances that may substantially decrease transmission of sexually transmitted infections (STI) including human immunodeficiency virus (HIV), are currently in clinical trials. They are being presented as woman-initiated prevention methods that have the potential to be used without partners’ knowledge. However, it is recognised that covert use may be challenging, due to th...

Vaginal microbicides, substances that may substantially decrease transmission of sexually transmitted infections (STI) including human immunodeficiency virus (HIV), are currently in clinical trials. They are being presented as woman-initiated prevention methods that have the potential to be used without partners' knowledge. However, it is recognised that covert use may be challenging, due to th...