We conducted the first systematic documentation of using oral polio vaccine (OPV) out of the cold chain during national immunization day (NID) campaigns in Mali. Using a crossover intervention design, vaccinators compared the transport of OPV in vaccine carriers with or without ice packs. Vaccine integrity was assured through monitoring vaccine vial monitor (VVM) status. Despite ambient tempera...

Background: Covid-19 pandemic has created havoc around the world and vaccination is an effective tool against this demon. Study of variations in administration daily doses vaccine at centre can help better resource management. Material & methods: This record based descriptive study was conducted among beneficiaries S. N. Medical College, Agra. Record wastage, different groups occurrence var...

In large workflow management systems (WfMS), it is particularly important to control workflows (WF) in an efficient manner. A very critical factor within this context is the resulting communication overhead. For this reason we have developed an approach for distributed WF control, which tries to keep the communication overhead low. In this paper, this approach is described and examined by means...

BACKGROUND Cigarette smoking (CS) is the most important risk factor for COPD, which is associated with neutrophilic airway inflammation. We hypothesize, that highly reactive aldehydes are critical for CS-induced neutrophilic airway inflammation. METHODS BALB/c mice were exposed to CS, water filtered CS (WF-CS) or air for 5 days. Levels of total particulate matter (TPM) and aldehydes in CS and...

The exact mechanism by which insulin reverses impaired wound healing is unknown. Previous investigators have shown that insulin is degraded in experimental wounds, suggesting that the action of insulin may be locally modified. The following study corroborates these findings and identifies the major proteinase responsible for insulin degradation in wound fluid (WF). Adult male Fisher rats were w...

Abstract The global introduction of COVID‐19 vaccines provided relief to the burden inflicted by SARS‐CoV‐2 virus. However, reports vaccine wastage are still apparent in some countries, particularly Philippines. This paper examines phenomenon with emphasis on factors related improper storage and distribution hesitancy whose roots may be traced a controversial rollout. discussion elaborates foll...

Growth factors such as platelet-derived growth factor (PDGF) exert potent effects on wound healing including the regeneration of tooth-supporting structures. This investigation examined the effect of the local delivery of PDGF-BB when combined with reconstructive periodontal surgery on local wound fluid (WF) levels of PDGF-AB, vascular endothelial growth factor (VEGF), and bone collagen telopep...

Shearer, Jeffry D., Cynthia F. Coulter, William C. Engeland, Richard A. Roth, and Michael D. Caldwell. Insulin is degraded extracellularly in wounds by insulindegrading enzyme (EC 3.4.24.56). Am. J. Physiol. 273 (Endocrinol. Metab. 36): E657–E664, 1997.—The exact mechanism by which insulin reverses impaired wound healing is unknown. Previous investigators have shown that insulin is degraded in ...