AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...

introduction: suspension of isolated hepatocyes is now being used in an increasing number of biochemical investigations, including drug metabolism and toxicity studies. isolated hepatocyes, retain many of the essential properties of the intact tissue including permeability charactreristics. material and methods: in this method at first liver is subjected to a nonrecirculating perfusion with cal...

AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...

current innovative lateral load carrying systems for tall buildings are those in which the lateral drift is limited to an allowable value without considerable influence on economy. this aim is achieved by using special systems capable of using maximum stiffness and strength capacity of individual structural elements. an effective structural solution in this respect is the use of outrigger brace...

Previous studies have shown that caffeine has beneficial effects on cognitive impairment in sleep deprived male rats. Therefore in the present study, we examined the effects of chronic caffeine administration on learning and memory impairments induced by sleep deprivation (SD) in the intact and ovarectomized (OVX) female rats. Two sets of animals including intact and OVX were randomly recruited...

  Objective: Selection of an appropriate shade of composite is critical in achieving an esthetic restoration. Different systems are used to assess and describe color parameters. This study aimed to assess the effect of color and thickness of Filtek Supreme (FS) and Premise (P) composite resins on correction of tooth discoloration.   Methods: In this in vitro experimental study, 10 anterior teet...