Hypocomplementemic urticarial vasculitis syndrome is an immune complex-mediated disease of unknown etiology. The clinical course is characterized by urticaria, conjunctivitis, joint pain, and hypocomplementemia. We here report a case of a child with hypocomplementemic urticarial vasculitis syndrome that progressed to nephritis. Renal biopsy was consistent with diffuse proliferative glomerulonep...

We describe a 33-year old man suffering from severe vertebral osteoporosis and urticaria pigmentosa due to systemic mast cell disease (SMCD). Because i.v. clodronate therapy could not prevent further vertebral fractures, an additional treatment with interferon alpha-2b was initiated. During 24 months of treatment, our patient had no further pain episodes, no new vertebral fractures were discove...

Background: Bullous pemphigoid (BP) is the most common autoimmune bullous disease and it primarily affects elderly population. It typically presents with tense bullae severe pruritus. Non-bullous a subtype of BP characterized by lacking typical formation different presentations including erythematous, eczematous, urticarial, polycyclic, targetoid, nodular, lichenoid, vesicular erythrodermic. Ai...

Biological agents targeting inflammatory skin diseases have dramatically overcome many of the limitations older oral therapeutic options. Among various biological agents, ixekizumab is a humanised monoclonal antibody that blocks activity IL-17A, which exhibited high efficacy against psoriasis. Although there are limited number cutaneous adverse reactions, biologic-induced type I allergic reacti...

Urticarial vasculitis (UV) is a protean disorder that can be triggered by myriad of causes although it often idiopathic. Treatment successful with corticosteroids and/or immunosuppressive drugs. However, when cause found, specific treatment the underlying problem or removal an offending agent will resolve symptoms. This report describes patient UV thyroid replacement, necessitated Hashimoto's t...

Both urticarial vasculitis and Schnitzler syndrome are serious diseases but a recently gained better understanding of their underlying pathomechanism allows better treatment options than only a decade ago.

BACKGROUND Urticarial dermatitis, which is characterised by persistent wheals with eczematous papules and plaques, is frequently misdiagnosed and difficult to treat. Patients commonly experience intolerable pruritus which may greatly affect their quality of life. OBJECTIVE The objective of this study is to characterize the clinical patterns of pruritus in patients with urticarial dermatitis a...

Clinically suspected recurrence of gastric carcinoid proved to be hypocomplementaemic urticarial vasculitis syndrome with