نتایج جستجو برای: undercarboxylated osteocalcin

تعداد نتایج: 4017  

Journal: :The Journal of clinical investigation 2014
Ryan C Riddle Thomas L Clemens

Recent studies have demonstrated that insulin stimulates bone cells to produce and activate osteocalcin, an endocrine hormone that increases the efficiency of glucose metabolism through its actions on the pancreas and other peripheral tissues. In this issue of the JCI, Wei and colleagues directly explore the contribution of insulin signaling in osteoblasts to the disturbances in whole-body gluc...

Journal: :Clinical chemistry 2000
A Caillot-Augusseau L Vico M Heer D Voroviev J C Souberbielle A Zitterman C Alexandre M H Lafage-Proust

BACKGROUND Microgravity induces bone loss by mechanism(s) that remain largely unknown. METHODS We measured biochemical markers related to bone remodeling in two cosmonauts before, during, and after 21- and 180-day space flights, respectively. RESULTS During both flights, type I procollagen propeptide and bone alkaline phosphatase decreased as early as 8 days after launch. Undercarboxylated ...

Journal: :Osteology 2021

Surprisingly little is known about the factors released from bone during resorption and metabolic roles they play. This paper describes what we have learned bone, mainly through study of burn injuries, play in post-burn metabolism. From these studies, know that calcium, phosphorus, magnesium, along with transforming growth factor (TGF)-?, are following resorption. Additionally, studies mice Kar...

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