Pneumocystis carinii expresses a surface glycoprotein called MSG. Different isoforms of MSG are encoded by a gene family spread over at least 15 telomeric sites. Only one locus, called UCS, supports the production of MSG mRNA. Previous studies showed that P. carinii populations from individual rats exhibited high degrees of diversity with respect to the MSG genes attached to the UCS locus. This...

While Electronic Medical Records (EMR) or prominent features within EMR have been hailed as an important step for advancing healthcare, a number of studies have noted that its introduction also brings unintended consequences (UCs) to healthcare organizations. According to the literature, the most disruptive type of unintended consequences is related to workflow issues, in that its occurrence wi...

Conventionally, many researchers have used both regression and black box techniques to estimate the unconfined compressive strength (UCS) of different rocks. The advantage of the regression approach is that it can be used to render a functional relationship between the predictive rock indices and its UCS. The advantage of the black box techniques is in rendering more accurate predictions. Gene ...

The U-curve optimization problem is characterized by a decomposable in U-shaped curves cost function over the chains of a Boolean lattice. This problem can be applied to model the classical feature selection problem in Machine Learning. Recently, the U-Curve algorithm was proposed to give optimal solutions to the U-curve problem. In this article, we point out that the U-Curve algorithm is in fa...

This experimental study investigates the strength characteristics of cemented super-fine unclassified tailings backfill (CSUTB) and its failure mechanism. Physical and chemical properties of tailings from the Zhongguan Iron Mine (ZGIM) were tested. A series of uniaxial compressive strength (UCS) tests was conducted to determine the relationships between UCS of CSUTB and three factors of cement-...

Two functions are proposed for the conserved family of UCS proteins: helping to fold myosin motor proteins and stimulating the motor function of folded myosins. We examined both functions in yeast. The fission yeast UCS protein (Rng3p) concentrates in nodes containing myosin-II (Myo2) and other proteins that condense into the cytokinetic contractile ring. Both the N-terminal (central) and C-ter...

the uniaxial compressive strength (ucs) of intact rocks is an important geotechnical parameter required for designing geotechnical and mining engineering projects. obtaining accurate estimates of the rock mass ucs parameter throughout a 3d geological model of the deposit is vital for determining optimum rock slope stability, designing new exploratory and blast boreholes, mine planning, optimizi...

OBJECTIVE Recently, heparin coated polytetrafluoroethylene (PTFE) shunts are available and are believed to improve inherent shunt problems such as thrombosis and excessive and incomplete neointima formation or occlusion. We aimed at comparing the potential histopathological differences in the neointima (in) between uncoated (UCS) PTFE shunts and heparin coated (HCS) PTFE shunts. MATERIALS AND...

Three days of fear conditioning that combines tactile stimulation of a row of facial vibrissae (conditioned stimulus, CS) with a tail shock (unconditioned stimulus, UCS) expands the representation of "trained" vibrissae, which can be demonstrated by labeling with 2-deoxyglucose in layer IV of the barrel cortex. We have also shown that functional reorganization of the primary somatosensory corte...