Background: Physical activity combined with some herbal supplementations can affect body energy metabolism, blood lipids and physical fitness levels. However, the effect of exercise training combined with fenugreek on lipid metabolism and body composition in patients with type2 diabetes is unknown. Objective: The aim of present study was to investigate the effects of eight weeks’ enduran...

INTRODUCTION There is increasing evidence on association between vitamin D insufficiency and diabetes, but the impact of vitamin D status on glycaemic status and vice versa, has not been well reported. Our aim was to investigate the level of 25-hydroxyvitamin D(25(OH)D) and the prevalence of vitamin D abnormalities in patients with diabetes mellitus (DM) type2 and in those without diabetes; and...

More than 1000 herbal products have been used by diverse cultures of the world to treat hyperglycemia and among them bitter melon (Momordica charantia) is one of the most popular herbal resource. The beneficial effects of bitter melon is not limited to hypoglycaemia only, but it also ameliorates diet induced obesity, insulin resistance and exhibit cardioprotective effects. The present study att...

Type2 Diabetes Mellitus (T2DM) is prevalent in a majority of population in India and approximately 30-35% of Indian populations are living with this syndrome. Many previous studies have linked Uric Acid (UA) to DM and some associations have been found out between them. As glycosylated Hemoglobin (HbA1c) is now routinely used to monitor diabetic control, this study was undertaken to find out if ...

The predominantly epithelial cell-derived cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) can promote CD4(+) Th2 cell-dependent immunity, inflammation, and tissue repair at barrier surfaces through the induction of multiple innate immune cell populations. IL-25 and IL-33 were previously shown to elicit four innate cell populations, named natural helper cells, nuocytes, innate ty...

Metformin therapy is a burst of interest in cancer chemoprevention and therapeutic strategies [1-4]. Epidemiological studies based on cohorts with type 2 diabetes revealed that metformin usage was associated with a reduced risk for various cancer, including breast, colorectal, prostate and pancreas cancers [5]. Meanwhile, the efficacy of cancer chemopreventive effect of metformin has achieved p...

Background: Diabetes mellitus, a group of metabolic disorder with multiple etiologies is characterized by chronic hyperglycaemia, induced deficiency insulin production and action. Prediabetes type hyperglycemia in which glycemic indices are higher than normal but lower the diabetes threshold. Objective: This study aims to assess impact bone markers (serum calcium, phosphorus alkaline phosphatas...

background: diabetes is a major cause of death. oxidative stress mainly caused by hyperglycemia is the primary reason of related complications. omega-3 fatty acids are prescribed in diabetes but the effect on antioxidant defense is controversial. this study investigated effects of omega-3 supplementation on antioxidant enzymes activity in type 2 diabetic patients. methods: a randomized, placebo...