background: the vascular function of angiotensin ii-type-2 receptors in adults is controversial. we sought their location and function in mouse aortic rings at young and old mice. materials and methods: male c57bl mice (aged 4 and 14 months) were killed by co2. the descending thoracic aorta was cleaned and dissected into rings. aortic rings were mounted in krebs’ solution at 37 °c and then setu...

conclusions the at1r a1166c polymorphism appeared not to be associated with the presence of acs in the population studied. background there are very limited data for iranian populations on the predisposing genetic factors for acute coronary syndrome (acs). results there was no statistical difference in the genotype frequency of patients and healthy subjects with regard to age and gender (p > 0....

conclusions regarding the results, it could be suggested that the reason for not being able to control diabetes was the existence of differences among viewpoints while by getting to know the obstacles for controlling diabetes from the viewpoints of the three studied groups, more effective planning for controlling diabetes could be possible. results the results of this research showed that there...

Background: The vascular function of Angiotensin II-type-2 receptors in adults is controversial. We sought their location and function in mouse aortic rings at young and old mice. Materials and Methods: Male C57Bl mice (aged 4 and 14 months) were killed by CO2. The descending thoracic aorta was cleaned and dissected into rings. Aortic rings were mounted in Krebs’ solution at 37 °C an...

Background and Objective: Several studies have found that diazepam decreases serum glucose. Meanwhile, glibenclamide is commonly used in diabetes treatment. The objective of this study was to survey the treatment impact of diazepam and glibenclamide on blood glucose and serum lipids in mice with type II diabetes. Materials and Methods: In this study, 32 male rats were divided into four groups,...

background: psychological and behavioral domains are important in coping with type ii diabetes. this study was conducted to assess supportive and coping obstacles in living with type ii diabetes among patients who visited hospitals affiliated to tehran university of medical sciences (tums). methods: this was a cross-sectional study with 600 subjects who participated in the study. data collectio...

In this article, we use a measure of expected true evidence for determine the required sample size in type-II censored experiments for obtaining statistical evidence in favor of one hypothesis about the exponential mean against another.

Background: Lead is one of the sustainable metals with devastating effects on many tissues. This study, examined the adverse effect of lead poisoning on the gene expression of collagen type II and osteocalcin by mesenchymal stem cells (MSCs) cultured in chondrogenic and osteogenic media, respectively. Methods: We used 18 male Wistar rats, divided in 3 groups. In addition to libitum feed as the...

In many life-testing and reliability studies, the experimenter might not always obtain complete information on failure times for all experimental units. One of the most common censoring schemes is progressive type-II censoring. The aim of this paper is characterizing the parent distributions based on Shannon entropy of progressive type-II censored order statistics. It is shown that the equality...

spinal muscular atrophy (sma) is an autosomal recessive neuromuscular disorder caused by homozygous deletion of the survival motor neuron gene 1 (smn1) in more than 90% of patients. according to the age of onset and severity of the disease, sma is classified into three groups: type i (severe), type ii (intermediate) and type iii (mild). as reported, the smn2 gene, centromeric copy gene, showed ...