recent studies suggested the role of white blood cells (wbcs) in the pathogenesis and complications of type 2 diabetes. increased wbc counts predict mortality in patients with chronic kidney disease (ckd). in this study alterations in wbc subpopulations in diabetic patients with non-dialysis dependent ckd are investigated. this was a cross-sectional study  on 376 participants, including   272 d...

docosahexaenoic acid (dha), as an omega-3 fatty acid, in a natural ligand of peroxisome proliferator-activated receptors (ppars). regarding the combinative effects of nutrigenomics and nutrigenetics and due to the lack of in vivo studies conducted using natural ligands of ppars, we aimed to evaluate the effects of dha supplementation on vascular function, telomerase activity, and pparγ-lxrα-abc...

patients and methods this prospective cohort study was performed on 90 diabetic type 2 patients with microalbuminuria, who were selected according to the consecutive sample selection method during 6 years. data were collected through regular and systematic measurements of serum albumin as the response variable and body mass index, systolic and diastolic blood pressure, the duration of diabetes,...

considering that mapk (mitogen- activated protein kinase) signaling pathway has an important role in the progression of inflammatory cytokine secretion in type 2 diabetes mellitus (t2dm), we have recently investigated the reported genetic polymorphism from genome wide association study in map3k1 (mitogen-activated protein kinase kinase kinase 1) in diabetes as an important member of mapk signal...

conclusions it can be concluded that the nettle extract can reduce blood glucose levels in diabetic mice, at least partly, by influencing the glut2 gene expression in mice liver. results the results showed that the nettle extract significantly decreased high levels of blood glucose (p < 0.001). the nettle extract also had a preventive effect on decrease in body weight. in addition, the results ...

background: transforming growth factor-beta 1(tgf-β1) t869c (rs1800470, the same below) gene polymorphism is notably relative with the development of diabetic nephropathy (dn)，and cc/ct genotype diabetic have higher frequency of than tt genotype diabetic. to find out individual risk factors in the two genotypes especially in susceptible genotype could provide more efficient and targeted prevent...

conclusions mobile phone text messaging increased adherence to diabetes therapy and improved the clinical outcome in saudi patients with type 2 diabetes. results in addition to significant improvement in patients’ knowledge, mean fasting blood glucose level improved from 8.60 ± 3.16 to 7.77 ± 3.11 mmol/l and mean hba1c decreased from 9.9% ± 1.8% to 9.5% ± 1.7%. objectives we conducted a study t...

background: diabetic men have been claimed to have lower serum free testosterone (ft) concentrations than non-diabetic men. the aim of this study was to investigate if serum ft, luteinizing hormone (lh), and follicle stimulating hormone (fsh) concentrations are different in patients with type 2 diabetes mellitus compared with healthy men and to identify factors associated with low serum testost...

background diabetic nephropathy is the most important cause of end stage renal disease (esrd). aldosterone is involved in renal damage through induction of fibrosis, inflammation and necrosis in the kidney tissue. previous studies have demonstrated that the combination of angiotensin receptor blocker (arb) and spironolactone (an anti-aldosterone drug) are efficient for albuminuria reduction. ob...