Recently we described a novel cell penetrating peptide, peptide for ocular delivery (POD) that could deliver small molecules including fluorescent dyes into retinal cells. The objective of the current study was to examine whether biologically relevant macromolecules such as proteins, genetically fused with POD could also be delivered into retinal tissues in vivo. We generated a POD-GFP fusion p...

BACKGROUND Postoperative delirium (POD) is a common and critical complication after cardiac surgery. However, the relationship between POD and postoperative physical frailty and the effect of both on long-term clinical outcomes have not been fully explored. OBJECTIVE We aimed to examine the associations among POD, postoperative frailty, and major adverse cardiac events (MACE). DESIGN This w...

BACKGROUND We have previously shown that a novel synthetic peptide for ocular delivery (POD) can efficiently compact DNA and deliver it to cells in vitro. This observation prompted us to develop use of POD as a nonviral vector in vivo. METHODS POD peptide was modified using poly(ethylene) glycol (PEG-POD) and used to compact DNA into nanoparticles that were then analysed using electron micros...

The aims of this paper are to present concept and results of an innovative educational model approach based on ergonomics involvement in industrial project. First we present Cross disciplinary Problem solving Workshop by answering three questions:1) What is a CPW: A partnership between Universities and one or several companies, purposes of it are first to increase health, well being, companies ...

A linear-solver preconditioner for the pressure systems in reservoir simulation based on Proper Orthogonal Decomposition (POD) is developed and investigated. The POD approach entails the use of a lower-dimensional space to approximate the original high-dimensional space. Essentially, POD can be considered as a Singular Value Decomposition (SVD) approach. The POD approximation error can be estim...

A reduced order model based on Proper Orthogonal Decomposition (POD) 4D VAR (Four-dimensional Variational) data assimilation for the parabolized Navier–Stokes (PNS) equations is derived. Various approaches of POD implementation of the reduced order inverse problem are studied and compared including an ad-hoc POD adaptivity along with a trust region POD adaptivity. The numerical results obtained...

Three genotypes of alfalfa viz. Medicago sativa (Zhongmu No. 1, Zhongmu No. 2) and M. varia (Caoyuan No. 3) grown in the filed were investigated for the contribution of pod wall and leaves by shading all pods and leaves on July 15, 20 and 25, respectively. Date was recorded for total pod weight (TPW), pod wall weight (PWW), seed weight per pod (SWP), seed number per pod (SNP) and single seed we...

It has previously been proposed that respiratory CO2 released from the embryo in grain legume pods is refixed by a layer of cells on the inner pod wall. In chickpea this refixation process is thought to be of significance to the seed carbon budget, particularly under drought. In this study it is reported that the excised embryo, seed coat, and pod wall in chickpea are all photosynthetically com...

A survey of the blood of twenty-two patients who had undergone hepatic resection was performed. Serum levels of alpha-2 plasmin inhibitor-plasmin complex initially decreased from 1.58 +/- 0.31 microgram/ml on the preoperative day (PREOP), to 0.92 +/- 0.14 mu/ml on the first postoperative day (POD 1), and then increased to 3.13 +/- 0.92 micrograms/ml on the seventh postoperative day (POD 7) (mea...

Secretory class III plant peroxidase (POD, EC 1.11.1.7) is believed to function in diverse physiological processes, including responses to various environmental stresses. To understand the function of each POD in terms of air pollutants and UV radiation, changes in POD activity and expression of 10 POD genes isolated from cell cultures of sweetpotato (Ipomoea batatas) were investigated in the l...