نتایج جستجو برای: tumor inhibition

تعداد نتایج: 715754  

Journal: Iranian Journal of Basic Medical Sciences 2020
Hojjat Sadeghi-aliabadi, Mansoureh Mirabdollahi, Shaghayegh Haghjooy Javanmard,

Objective(s): Controversial results have been reported regarding the anti-tumor properties of extracellular vesicles derived from mesenchymal stem cells (MSCs). The present study was conducted to evaluate whether secretome derived from Human Wharton’s jelly mesenchymal stem cells (hWJMSCs) may stimulate or inhibit breast cancer growth in vitro and in vivo.<st...

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Journal: :iranian biomedical journal 0
احسان خداپسند ehsan khodapasand نرگس جعفرزاده narges jafarzadeh فرید فرخی farid farrokhi بهنام کمالی دهقان behnam kamalidehghan مسعود هوشمند massoud houshmand

background: bax and bcl-2 are the major members of bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. methods: in this study, the relative level of mrna expression of bax and bcl-2 genes was deter...

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Journal: :medical journal of islamic republic of iran 0
noushin jalayer naderi department of oral and maxillofacial pathology, faculty of dentistry, shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه شاهد (shahed university) farrokh tirgari pathology department, institute cancer, tehran university of medical sciences, tehran, iran. hosp_cancer@tums.ac.ir 3. dds, shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) zahra keshavarz shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه شاهد (shahed university)

background: new blood vessels formation is a critical step in tumor progression. vascular density affects the clinical outcome and prognosis of malignant tumors. the aim of this study was to investigate the relation between the vascular endothelial growth factor (vegf) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (oscc).   method...

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Journal: :OncoImmunology 2015

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Journal: :Neuro-oncology 2023

Abstract Diffuse Midline Gliomas (DMG) is the leading cause of brain tumor-related death in children. Currently, radiation only treatment that offers transient benefit but almost all DMG relapse due to radioresistance. Compared normal tissue, are hypo-perfused with tumor cells being exposed hypoxia, a low oxygen microenvironment serves as potent barrier effective radiotherapy. Biguanides hypogl...

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Journal: :Journal of Biological Chemistry 2002

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Journal: :Journal of Clinical Investigation 2013

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Journal: :Annals of Oncology 2017

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Journal: Medical Journal of Islamic Republic of Iran 2016
Farrokh Tirgari, Noushin Jalayer Naderi, Zahra Keshavarz,

Background: New blood vessels formation is a critical step in tumor progression. Vascular density affects the clinical outcome and prognosis of malignant tumors. The aim of this study was to investigate the relation between the Vascular Endothelial Growth Factor (VEGF) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (OSCC). &nbsp...

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Journal: :Current Medical Research and Opinion 2015

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