Background & Objective: In vascular (vasculogenic) mimicry (VM), tumoral cells mimic the endothelial cells and form the extracellular matrix-rich tubular networks. It has been proposed that VM is more extensive in aggressive tumors. This study was designed to investigate the rate of VM expression in the stromal cells of invasive ductal carcinoma (IDC) and to find its relationsh...

introduction: natural killer (nk) cells, of which cd56 is a specific marker, play an important role in host defense against tumors. cancer stem cells, of which aldehyde dehydrogenase isoform 1 (aldh1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. we aimed to evaluate the expression of aldh1 and cd56 in common salivary g...

objective adenoid cystic carcinoma (acc) is a rare malignant tumor originating from the salivary glands. it’s rather bland histological appearance that masks its ultimate biological aggressiveness. evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. the aim o...

background: the present study was undertaken to investigate the correlation of epidermal growth factor receptor (egfr) expression with grade of transitional cell carcinoma (tcc). methods: tumor samples of 75 patients from mostafa khomaini hospital with transitional cell carcinoma of the bladder were analyzed by immunohistochemistry for expression of egfr. in this context, we assigned the bladde...

Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...

background and objectives: rcc is one of the most common genitourinary cancers. accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. p53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle arrests after dna damage and apoptosis. presence of mutated p53 protein in tumors has been rel...

abstract   synchronous upper urinary tract tumor and superficial bladder tumor are uncommon. this is a report of a 62- year- old man presented with episode of painless gross hematuria and flank pain. we worked him up and found a left renal mass and bladder lesion. he underwent nephrectomy and tur-bt, and the pathology report of both showed a high grade urothelial transitional cell carcinoma. th...

objective: gliomas are the most common primary brain tumors, and have been ranked as the fourth leading cause of cancer death. tumor mesenchymal-like stem cells (tmscs) contribute to the aggressive behavior of glial tumors by providing a favorable microenvironment for the malignant cells. the aims of our study were to identify differential proteome of tmscs derived from low vs. high grade gliom...

Objective Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from the salivary glands. It’s rather bland histological appearance that masks its ultimate biological aggressiveness. Evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. Ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. The aim ...

Introduction: Natural killer (NK) cells, of which CD56 is a specific marker, play an important role in host defense against tumors. Cancer stem cells, of which aldehyde dehydrogenase isoform 1 (ALDH1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. We aimed to evaluate the expression of ALDH1 and CD56 in common salivary g...