The small genome of Arabidopsis contains at least nine expressed beta-tubulin (TUB) genes, in contrast to the large genomes of vertebrate animals, which contain a maximum of seven expressed beta-tubulin genes. In this study, we report the structures of seven new TUB genes (TUB2, TUB3, TUB5, TUB6, TUB7, TUB8, and TUB9) of Arabidopsis. The sequences of TUB1 and TUB4 had been reported previously. ...

OBJECTIVE Human activities associated with aerosol-generating hot water sources are increasingly popular. Recently, a hypersensitivity pneumonitis (HP)-like granulomatous lung disease, with non-tuberculous mycobacteria from exposure to hot water aerosols from hot tubs/spas, showers, and indoor swimming pools, has been described in immunocompetent individuals (also called "hot tub lung"). Our ob...

This study investigated the functional performance of two major subtypes of dementia, Alzheimer's disease (AD) and vascular dementia (VaD), by the Functional Independence Measure (FIM), and to understand the need for assistance in performing activities of daily living. The subjects comprised 64 AD and 21 VaD patients who were recruited from two epidemiologic studies of dementia with a total of ...

The typical bathtub curve and its “standard”shape have been widely accepted as an engineering tool in reliability management and training. However, some recent researches reveal that the typical theory of ‘bathtub curve’is not so convincing in some situations. Therefore, a critical discussion is developed to research the bath-tub curve along three significant periods of bath-tub; i.e. infant mo...

Background: The newborn’s first bath, performed in Neonatal Intensive Care Units (NICU), is believed to be a stressful situation, especially for the premature infants. As a developmental care approach, swaddle bathing is a low-stress bathing method for vulnerable preterm neonates. Given the limited number of the studies examining this bathing method, the present study was conducted with the aim...

OBJECTIVES To examine environmental feature utilization (EFU) and the types and prevalence of performance difficulties during a videotaped bath transfer and to determine the personal characteristics associated with total EFU and performance difficulties. DESIGN Cross-sectional analysis. SETTING Two congregate housing facilities in southeastern Michigan. PARTICIPANTS Eighty-nine older adul...

The aim of this study was to examine the effect of age and spa treatment (i.e. combined sauna, cold water immersion, and jacuzzi) on match running performance over two consecutive matches in highly trained young soccer players. Fifteen pre- (age 12.8 ± 0.6 years) and 13 post- (15.9 ± 1 y) peak height velocity (PHV) players played two matches (Matches 1 and 2) within 48 h against the same opposi...

Multidrug resistance (MDR) is a major hindrance to curative chemotherapy of various human malignancies. Hence, novel chemotherapeutics must be evaluated for their recognition by MDR efflux transporters. Herein we explored the cytotoxic activity of synthetic tubulysin B (Tub-B, EC1009) derivatives (Tub-B-hydrazide/EC0347 and Tub-B bis-ether/EC1820), and their recognition by the MDR efflux transp...

To the Editor: I read with interest the report by Mangione et al. regarding Mycobacterium avium infection in a Colorado family who used an inadequately sanitized hot tub (1). The authors noted that the source of the M. avium complex was not clear, although the reservoir did appear to have been the hot tub. Twenty years ago, I helped treat a patient with a local infection caused by M. fortuitum ...