Objective(s) The immunoadjuvant potential of cross-linked dextran microspheres (CDM) as absorption enhancer and Quillaja saponins (QS) as immunomodulator adjuvant was evaluated. Materials and Methods CDM loaded or tetanus-mixed toxoid (TT) or Quillaja saponin (QS) were nasally administered to rabbits in dry powder form, three times in 2 weeks interval and serum IgG and nasal lavage sIgA tite...

BACKGROUND The group A meningococcal conjugate vaccine, PsA-TT, uses tetanus toxoid (TT) as a carrier protein (PsA-TT). TT as a carrier protein in other conjugate vaccines is known to be immunogenic and generates a robust anti-TT response. METHODS Clinical studies in Africa assessed whether PsA-TT generated tetanus serologic responses when tested in African populations (toddlers to adults). S...

introduction and aims: tt virus (ttv) is a dna virus and is proposed as a potential cause of non-a to e hepatitis. we aimed to investigate, for the first time, the prevalence of ttv in iranian healthy blood donors. materials and methods: three hundred and twelve healthy iranian blood donors were randomly selected and tested for ttv dna by the seminested polymerase chain reaction method. serum a...

background: in 1997, a novel dna virus was isolated from the serum of a patient in japan

The meta-analysis aimed to investigate the correlation between the polymorphism of the vitamin D receptor (VDR) TaqI and susceptibility of colorectal cancer.Studies were extracted from the electronic databases of PubMed and Embase. The balance of heredity was estimated by the Hardy-Weinberg equilibrium test, and heterogeneity was assessed by Cochran Q statistics and I test. Four assessed models...

Background: Tibial tuberosity-trochlear groove distance (TT-TGD) measurements play a decisive role in evaluatingpatellofemoral joint disorders. However, the prevalence of pathological TT-TGD among patients with patellofemoralpain remains unclear. The purpose of this study was to compare the size of TT-TGD among patients with patellofemoralpain syndrome (PFPS) and those with no history of patell...

We explore the relation between dust and several fundamental properties of simulated galaxies using Dusty SAGE semi-analytic model. In addition to tracing standard galaxy properties, also tracks cold mass in interstellar medium (ISM), hot halo ejected by feedback activity. Based on their ISM content, we divide our into two categories: dust-poor dust-rich. split group subgroups: dust-rich (the l...

SUMMARY The computation of the Love numbers (LNs) for a spherically symmetric self-gravitating viscoelastic Earth is classical problem in global geodynamics. Here we revisit numerical evaluation loading and tidal LNs static limit an incompressible planetary body, adopting Laplace inversion scheme based upon Post-Widder formula as alternative to traditional normal modes method. We also consider,...