OBJECTIVE Turner syndrome (TS) is the most common sex chromosome abnormality in females. Previous research has indicated a high prevalence of celiac disease (CD) in TS, but data have mostly been limited to case series at tertiary centers. We aimed to examine the risk for CD in individuals with TS compared with the general population. METHODS This Swedish nationwide case-control study included...

Two important polymorphisms of folate cycle enzymes, methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase (TS) enhancer region (TSER) 28-bp tandem repeat, are related to risk of various types of cancer, including brain tumors, although there are few studies on this subject. A case-control study of these two polymorphisms in astrocytomas of different grades was carried out ...

Only a few cases of Turner syndrome (TS) with ischemic stroke have been reported. Various arteriopathies of the cerebral arteries, including fibromuscular dysplasia, congenital hypoplasia, moyamoya syndrome, and premature atherosclerosis have been assumed to be the cause of ischemic stroke in TS. There has been no case report of a TS patient presenting with an embolic stroke pattern without any...

Hyperhomocysteinemia is a risk factor for cardiovascular disease and occurs frequently in end-stage renal disease (ESRD), but its pathogenesis is poorly understood. We aimed to evaluate one-carbon flux rates of methionine and homocysteine (Hcy) in ESRD patients and healthy controls. Transmethylation (TM), remethylation (RM), and transsulfuration (TS), as well as Hcy clearance by TS (i.e., TS/pl...

Aim of study: This study aimed to improve some physical, mechanical properties, and fire resistance wood-plastic composites (WPCs) with short glass fiber reinforcement (SGFR). Materials Methods: The WPCs were reinforced different ratios (SGF). effect on the water absorption (WA), thickness swelling (TS) as physical flexural strength, modulus elasticity, tensile strength properties determined. p...

Bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) is a chemically and genetically validated target in African trypanosomes, causative agents of sleeping sickness in humans and nagana in cattle. Here we report the kinetic properties and sensitivity of recombinant enzyme to a range of lipophilic and classical antifolate drugs. The purified recombinant enzyme, expressed as a fusi...

A genetic susceptibility to acute lymphoblastic leukemia (ALL) has been suggested. The present study was conducted to examine the influence of interaction between methylenetetrahydrofolate reductase (MTHFR) variants and thymidylate synthase (TS) 28base pair (bp) repeat polymorphism on the risk of pediatric ALL. Sixty eight ALL children with the mean age of 8.19±4.0 years and 70 ageand sex-match...

The aim of this study was to determine the levels of six polychlorinated biphenyls (referred to as PCB-28, PCB-52, PCB-101, PCB-138, PCB-153 and PCB-180, according to the IUPAC) in freshwater fish from the Zagreb area. A total of 216 samples was collected from five sites: from the Sava River upstream of Zagreb, in Zagreb, and downstream of Zagreb, from Lake Jarun, and from five fishponds from t...

We reported final height data of collected 28 cases with Turner Syndrome (TS) were confirmed chromosomal analysis during growth hormone therapy and late estrogen therapy. Participants allocated into one 3 Groups, Group A: 11 patients aged between 15-18 years-old, group B: 10 -15 C: 7 younger than years-old. In contrast to the duration & presentation, B showed a significantly higher mean (14...

This study examined performance on a battery of neuropsychological tests in a sample of 28 patients with Tourette’s syndrome (TS). Test scores were converted to age-corrected T-scores to control for the effect of age on test performance. The frequency of abnormal test performances was variable, but more frequent on motor and sensory tasks. Symptom severity as measured by the Tourette Syndrome G...