In this study, we aimed to determine the contribution of peroxynitrite-dependent sulfhydryl group (SH) oxidation to the contractile dysfunction in permeabilized left ventricular human cardiomyocytes using a comparative approach with the SH-oxidant 2,2'-dithiodipyridine (DTDP). Additionally, different antioxidants: dithiothreitol (DTT), reduced glutathione (GSH) or N-acetyl-L-cysteine (NAC) were...

Since hydraulic fractures exhibit a strong tendency to propagate in a plane normal to the least principal stress, the preferred plane of propagation under thrust stress regime (Sh > Sv) conditions is horizontal. This can lead to complications in applying the hydrofracture stress measurement technique as horizontal fractures do not directly sample the horizontal stress field. Recent experiences ...

In Shaker K(+) channel, the amino terminus deletion Delta6-46 removes fast inactivation (N-type) unmasking a slow inactivation process. In Shaker Delta6-46 (Sh-IR) background, two additional mutations (T449V-I470C) remove slow inactivation, producing a noninactivating channel. However, despite the fact that Sh-IR-T449V-I470C mutant channels remain conductive, prolonged depolarizations (1 min, 0...

Powder metallurgy allows designers of electric motors to implement new magnetic circuit structures. A relatively new concept is the use of a magnet system consisting of various types of magnets on one rotor, for example sintered and bonded magnets. This concept has been applied to the design and manufacture of the four-pole rotor of a synchronous motor with 400 W power and a rotational speed of...

Experiments were performed to determine the influence of exercise training by swimming on cardiovascular autonomic control and renal morphology in spontaneously hypertensive rats (SHR) and Wystar-Kyoto (WKY) rats. Sedentary normotensive (SN), trained normotensive (TN), sedentary hypertensive (SH), and trained hypertensive (TH) rats were included in this study. Arterial pressure (AP), heart rate...

Hardening of SD (8 and 12 hrs) and LD (18- and 24-hr photoperiods) cabbage plants in stages at temperatures starting with + 5 degrees and ending with - 3 degrees led to the following changes:Soluble protein plus nonprotein N showed a net increase only in the SD plants. In both SD and LD plants, it decreased to a minimum toward the end of the first stage of hardening, increased to a maximum in t...

The Pacific oyster, Crassostrea gigas , is a species in which true male and female well as hermaphrodite individuals have been reported. Among the latter, most are sequential, with one or more sex changes throughout their live, while few (<2%) simultaneous hermaphrodites (SH) may self-fertilize. Sex determinism its functional bases remain unclear this species. In study, SH oyster was found amon...

Thiol group functionalized silica-coated magnetic nanoparticles (Si-MNPs@SH) were synthesized for rapid and selective magnetic field-based separation of mixed proteins. The highest adsorption efficiencies of binary proteins, bovine serum albumin (BSA; 66 kDa; pI = 4.65) and lysozyme (LYZ; 14.3 kDa; pI = 11) were shown at the pH values corresponding to their own pI in the single-component protei...