Dilation of pupil has been a major component diagnostic eye examination inOptometric practice. Although mydriatic agents are used in clinical procedures, thereis no satisfactory explanation for the preference one over another. This studycompared dilating effect three different on dark irides ofninety healthy subjects; comprising 48 males and 42 females aged 16-30 (mean age18.77±0.52) years divi...

Background: To compare mydriasis obtained with Tropicamide 0.8% and phenylephrine 5% in type 2 diabetic and non diabetic patients. Materials & Methods: Observational study done in Ophthalmology OPD during January to May 2013. 100 eyes from 50 patients (30 type 2 diabetic and 20 non diabetics) were dilated with tropicamide 0.8% w/v and phenylephrine 5% w/v. In both groups pupil diameters were me...

BACKGROUND: Patients with Alzheimer's disease (AD) reportedly exhibit hypersensitivity to much diluted tropicamide solution (0.005%), a M4 muscarinic receptor antagonist. Therefore intraocular application of 0.005% tropicamide may be useful for screening dementia. The aim of this study was to simplify the pupil response test by using a new image analyzing system, which consists of a cheap, simp...

BACKGROUD To evaluate the manifestations of increased esodeviation under cycloplegia with 0.5% tropicamide and 0.5% phenylephrine in children with hyperopia and esotropia. METHODS We reviewed the medical record of 34 children with hyperopia and esotropia who underwent a prism alternate cover test before and after instillation of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephri...

PURPOSE To analyze whether preinstillation of lignocaine potentiates mydriasis by tropicamide in dark eyes and to determine possible mechanisms for this effect. METHODS This investigation was conducted in two phases, the first being a double-masked, placebo-controlled, randomized clinical trial, enrolling 60 healthy dark brown eyes in 30 subjects aged 7 to 58 years. The control eye received a...

accurate measurement of refractive error in uncooperative patients and young children, requires cycloplegia. the aim of the present study was to determine whethere cyclopentolate by itself or in combination with 4 times instillation of atropine can be used as a substitute for 10 times instillation of atropine. from 1994 to 1996, 39 patients aged 2-12 years were included in this study. cyclopleg...

drops from neurologic disease, pilocarpine, a parasympathomimetic agent, is safe and reliable. It causes ·constriction of the iris sphincter unless atropine or an·other postsynaptic blocker, such as tropicamide, the substance involved in this case, has been used. Physostigmine salicylate (Antilirium) was not used, · but it is effective in treating anticholinergic intoxica.' tion when administer...

Background: Scotopic function is an important marker of many retinal diseases and is increasingly used as an outcome measure in clinical trials, such as those investigating gene therapy for Lebers congenital amaurosis. Scotopic visual function has traditionally been measured using an adapted perimetry system such as the Humphrey field analyser (HFA). However this system does not control for fix...

Altogether 85 eyes from patients at risk to the development of closed-angle glaucoma were dilated with either parasympatholytic or sympathomimetic drugs. Of 21 eyes dilated with cyclopentolate 1/2%, 9 developed angle closure and a significantly raised pressure at some stage during dilatation and subsequent miosis. Of 58 eyes dilated with tropicamide 1/2%, 19 developed angle closure and a signif...

The time courses of changes in the effects of topical pilocarpine and tropicamide on the index of the blood-aqueous barrier permeability to plasma protein (Pin) were determined in normal volunteers. Before and after drug instillation in one eye, protein concentration in the anterior chamber (Ca) was determined from aqueous flare intensity with a laser flare-cell meter and from aqueous flow by f...