Background: To compare mydriasis obtained with Tropicamide 0.8% and phenylephrine 5% in type 2 diabetic and non diabetic patients. Materials & Methods: Observational study done in Ophthalmology OPD during January to May 2013. 100 eyes from 50 patients (30 type 2 diabetic and 20 non diabetics) were dilated with tropicamide 0.8% w/v and phenylephrine 5% w/v. In both groups pupil diameters were me...

BACKGROUND: Patients with Alzheimer's disease (AD) reportedly exhibit hypersensitivity to much diluted tropicamide solution (0.005%), a M4 muscarinic receptor antagonist. Therefore intraocular application of 0.005% tropicamide may be useful for screening dementia. The aim of this study was to simplify the pupil response test by using a new image analyzing system, which consists of a cheap, simp...

BACKGROUD To evaluate the manifestations of increased esodeviation under cycloplegia with 0.5% tropicamide and 0.5% phenylephrine in children with hyperopia and esotropia. METHODS We reviewed the medical record of 34 children with hyperopia and esotropia who underwent a prism alternate cover test before and after instillation of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephri...

PURPOSE To analyze whether preinstillation of lignocaine potentiates mydriasis by tropicamide in dark eyes and to determine possible mechanisms for this effect. METHODS This investigation was conducted in two phases, the first being a double-masked, placebo-controlled, randomized clinical trial, enrolling 60 healthy dark brown eyes in 30 subjects aged 7 to 58 years. The control eye received a...

accurate measurement of refractive error in uncooperative patients and young children, requires cycloplegia. the aim of the present study was to determine whethere cyclopentolate by itself or in combination with 4 times instillation of atropine can be used as a substitute for 10 times instillation of atropine. from 1994 to 1996, 39 patients aged 2-12 years were included in this study. cyclopleg...

drops from neurologic disease, pilocarpine, a parasympathomimetic agent, is safe and reliable. It causes ·constriction of the iris sphincter unless atropine or an·other postsynaptic blocker, such as tropicamide, the substance involved in this case, has been used. Physostigmine salicylate (Antilirium) was not used, · but it is effective in treating anticholinergic intoxica.' tion when administer...

Altogether 85 eyes from patients at risk to the development of closed-angle glaucoma were dilated with either parasympatholytic or sympathomimetic drugs. Of 21 eyes dilated with cyclopentolate 1/2%, 9 developed angle closure and a significantly raised pressure at some stage during dilatation and subsequent miosis. Of 58 eyes dilated with tropicamide 1/2%, 19 developed angle closure and a signif...

The time courses of changes in the effects of topical pilocarpine and tropicamide on the index of the blood-aqueous barrier permeability to plasma protein (Pin) were determined in normal volunteers. Before and after drug instillation in one eye, protein concentration in the anterior chamber (Ca) was determined from aqueous flare intensity with a laser flare-cell meter and from aqueous flow by f...

OBJECTIVE To compare the mydriatic effect of lower conjunctival fornix packing to conventional instillation of eyedrops containing 2.5% phenylephrine and 1% tropicamide in premature infants undergoing examination for retinopathy of prematurity. METHODS The patients were randomized to receive either conventional instillation of mydriatic drops or lower conjunctival fornix packing in one eye an...

PURPOSE To determine by means of fluorophotometry whether pharmacologic dilation of the pupil can interfere with the measurement of aqueous flow. METHODS Ten normal human volunteers underwent dilation with tropicamide, phenylephrine, and a combination of the two drugs. Before and after dilation, the rate of aqueous flow was measured by the rate of disappearance of fluorescein from the cornea ...