The objective of the study is to evaluate Olibanum resin, a natural resin polymer as matrix polymer for controlled release tablets and to design matrix tablets of diclofenac for controlled release. Matrix tablets of diclofenac were formulated employing Olibanum resin in different proportions of drug and polymer and the tablets were evaluated for drug release kinetics and mechanism. Two diluents...

In the following article the indications for the use of steroids in asthma are considered. The risks attendant upon such treatment are discussed. A comparison is made between the effects of the naturally occurring preparations and some of the modern synthetic analogues. The following table shows roughly equivalent doses of the various oral steroid preparations, so that comparable doses can read...

In the following article the indications for the use of steroids in asthma are considered. The risks attendant upon such treatment are discussed. A comparison is made between the effects of the naturally occurring preparations and some of the modern synthetic analogues. The following table shows roughly equivalent doses of the various oral steroid preparations, so that comparable doses can read...

background:ecstasy, mainly composed of 3,4-methylenedioxymethamphetamine (mdma), is one of the most popular addictive synthetic drugs. this study was aimed to investigate the amount of mdma in the ecstasy tablets seized in west azerbaijan province, northwest iran and also to assess the relationship between the physicochemical and morphological characteristics of the tablets. methods: mdma conte...

the physicochemical properties of Iranian acetyl salicylic acid(ASA) tablets,including the products of 10 manufacturers with 14 products,from each 3 batches,totally 42 products have been studied.the properties under investigation are hardness,friability percintage,humidity percentage,free salicylic acid,content uniformity,amount of ASA disintegration time,and released percentage.the results ind...

In this study, attempts were made to evaluate the effect of various acrylic acid based Carbopols on the release profile of a beta-adrenoreceptor blocking drug, propranolol HCl, from matrix-type tablets invitro. For this purpose, tablets containing 160 mg of propranolol HCl along with various amounts of Carbopols 934 (C934), 971 (C971), 974 (C974) and Pemulen (Pem) were prepared using the wet gr...

The clinical application of sirolimus (SRL) as an immunosuppressive agent is largely hampered by its narrow therapeutic range. This study focused on developing SRL tablets with a sustained release profile for better safety. SRL was highly water insoluble and its solubility has been efficiently enhanced by preparing self-microemulsifying drug delivery system (SMEDDS). The SRL-SMEDDS was physical...

Aluminum plastic foamed mask package is commonly used for the packaging of tablets in the pharmaceutical companies and defective tablets can be produced during the production of the packaging. This paper studies several key algorithms of defect detection for tablets in aluminum and plastic package and designs the autodetection software which applies an image processing and recognition technolog...

In this study 50 samples of ecstasy tablets seized in Iran during the period of 2007 through 2008 were examined and their physical characteristics (appearance, marking, scored/not scored, color, weight, diameter, thickness) were determined. In order to determine the chemical characteristics of these tablets, color tests (Marquis test, Simon's test, Chen's test and Gallic acid test), Thin Layer ...