1. The occurrence of a novel series of triterpenoid carotenes in Streptococcus faecium UNH 564P is reported. 2. This series, which comprises the C(30) analogues of phytoene, phytofluene, zeta-carotene, 7,8,11,12-tetrahydrolycopene and neurosporene, appears to be analogous to the C(40) Porter-Lincoln series and a pathway of triterpenoid carotene dehydrogenation is proposed to account for the for...

Two new compounds, the 6-oxo oleanane-type triterpenoid uncarilic acid, and its 5,6-secotriterpenoid derivative, secouncarilic acid, were isolated from the hooks and stems of Uucaria sessilifructus together with seven known ursane-type triterpenoids. Uncarilic acid is the second 6-oxo oleanane-type triterpenoid ever reported, while secouncarilic acid is the first oleanane-type 5,6-secotriterpen...

Anti-mycobacterial bioactivity of non polar compounds from red algae Euchema spinosum of Barang Lompo Island was studied. A triterpenoid carbocylic acid has been isolated from the chloroform fraction of Euchema spinosum, and its structure was determined by spectroscopic evidences including IR and 2D NMR and compared to previous data. The isolate was active against Mycobacterium tuberculosis at ...

Saponins are glycosides with triterpenoid or spirostane aglycones that demonstrate various pharmacological effects against mammalian diseases. To promote the research and development of anticancer agents from saponins, this review focuses on the anticancer properties of several typical naturally derived triterpenoid saponins (ginsenosides and saikosaponins) and steroid saponins (dioscin, polyph...

Phytochemical investigation of the rhizomes and roots of Ligularia veitchiana afforded a new triterpenoid saponin and two known neolignans named liguveitoside B (1), citrusin A (2) and citrusin B (3), respectively. This is the first demonstration of the occurrence of a 8-O-4’ neolignan and the second report on the isolation of triterpenoid saponin in the genus Ligularia. Their structures were e...

BACKGROUND Anemone flaccida Fr. Shmidt (Ranunculaceae), commonly known as 'Di Wu' in China, is a perennial herb with limited distribution. The rhizome of A. flaccida has long been used to treat arthritis as a tradition in China. Studies disclosed that the plant contains a rich source of triterpenoid saponins. However, little is known about triterpenoid saponins biosynthesis in A. flaccida. RE...

Sea cucumbers are characterized by their content in holothurins, triterpenoid glycosides that are responsible for the toxicity of these echinoderms. Nearly 100 holothurins isolated in the last twenty years are grouped into three main aglycone structural types: 3p-hydrox>iiolost-9(ll)-ene, 3p-hydrox5*iolost-7-ene and nonholostane based aglycones. This communication offers a general view of the s...

Bioassay-guided fractionation of the dichloromethane extract of the leaves of Marila pluricostata led to the isolation of 2alpha,3beta-dihydroxy-D:A-friedoolean-28-oic acid (pluricostatic acid), a new friedelane triterpenoid, (1), ten known triterpenoids and three sterols. Their chemical structures were elucidated through spectroscopic analysis. The less polar fractions, on GC/MS analysis and c...

many different plant species synthesize triterpenoid saponins as part of their normal programme of growth and development. examples include plants that are exploited as sources of drugs. interest in these molecules stems from their medicinal properties, antimicrobial activity, and their likely role as determinants of plant disease resistance. daisy (bellis perennis l.) accumulates triterpenoid ...