The optimal antithrombotic regimen remains controversial in patients taking oral anticoagulation (OAC) undergoing coronary stenting. This study sought to compare efficacy and safety outcomes of triple therapy (OAC, aspirin, and clopidogrel) vs dual therapy (clopidogrel with aspirin or OAC) in these patients. We hypothesize OAC plus clopidogrel could be the optimal regimen for patients with indi...

Objective: Standard triple therapy for H. pylori eradication is no longer effective in many countries including Thailand. This study was designed to evaluate the efficacy of adding bismuth and probiotic supplement to standard triple therapy for H. pylori eradication in Thai patients. Method: This prospective single-center study was conducted in Thailand. H pylori infected gastritis patients wer...

PURPOSE The efficacy of EMG-biofeedback and low-frequency electrical stimulation for the treatment of anal incontinence has not been proven. Our purpose was to evaluate a novel therapeutic concept, termed triple target treatment, which combines amplitude-modulated medium-frequency stimulation and EMG-biofeedback. METHODS Patients with anal incontinence were randomly assigned to the triple tar...

BACKGROUND Eradication of Helicobacter pylori with antimicrobials was recommended by a recent NIH consensus panel for all infected patients with peptic ulcer disease. The precise regimen that should be used for eradication of the infection remains uncertain because of the variety of regimens described, variable results with the regimens, and difficulties in predicting drug compliance outside cl...

aim : the aim of this study was to compare the half-dose and full-dose triple therapy regimens for helicobacter pylori ( hp ) eradication in patients with end-stage renal disease. background : h. pylori is one the most important causes of dyspepsia in patients with end-stage renal disease (esrd). patients and methods : sixty-six patients with esrd were enrolled in the study with hp infection an...

background and purpose: successful treatment of helicobacter pylori infection causes not only eradication of pathogen, but also prevents the associated diseases such as peptic ulcer, gastric carcinoma and lymphoma. the aim of this study was to evaluate the efficacy of 7 days triple therapy as a lowest drug resistance, shortest duration and fewer numbers of drugs in children. materials and metho...

background : the purpose of this study was to evaluate the effect of apple cider vinegar plus ppi-based triple therapy on eradication of helicobacter pylori (h.pylori) infection. materials and methods : 116 patients with h. pylori infection were included in this randomized clinical trial. patients in control group (n=59) received amoxicillin, clarithromycin, and pantaprazole twice daily. patien...

BACKGROUND Helicobacter pylori (H. pylori) gastric infection is a main cause of inflammatory changes and gastric cancers. OBJECTIVE The aim of this study was finding the effects of curcumin on oxidative stress and histological changes in chronic gastritis associated with H. pylori. METHODS In a randomized clinical trial, patients were divided into two groups: a standard triple therapy group...

OBJECTIVE Subjects (n = 188) with type 2 diabetes and inadequate response to two oral medications (A1C >8.0%) were randomly assigned to treatment with either a third oral medication or an insulin 70/30 mix b.i.d. plus metformin for a comparison of efficacy, safety, and cost. RESEARCH DESIGN AND METHODS The protocol called for aggressive dose titration to achieve target values of fasting blood...