The influence of 1-(2-trifluoromethylphenyl)imidazole (TRIM) and 3-bromo-7-nitroindazole (3-Br-7-NI), potent and relatively selective inhibitors of neuronal nitric oxide (NO) synthase, on the antinociceptive and anticonvulsive effects of diazepam and clonazepam was investigated in mice. The effects were assessed in the writhing test and pentetrazole-induced seizures, respectively. The antinocic...

Evidence from a variety of sources indicate that allogeneic blood transfusions can induce clinically significant immunosuppression, as well as other effects, in recipients. This clinical syndrome is generally referred to in the Transfusion Medicine literature as transfusion-associated immunomodulation, or TRIM. TRIM has been linked to an improved clinical outcome in the setting of renal allogra...

Trauma risk management (TRiM) is an intensive posttraumatic stress disorder (PTSD) psychoeducational management strategy based on peer-group risk assessment developed by the UK Royal Navy (RN). TRiM seeks to modify attitudes about PTSD, stress, and help-seeking and trains military personnel to identify at-risk individuals and refer them for early intervention. This quasiexperimental study found...

The software TrIm offers implementations of tropical implicitization and tropical elimination, as developed by Tevelev and the authors. Given a polynomial map with generic coefficients, TrIm computes the tropical variety of the image. When the image is a hypersurface, the output is the Newton polytope of the defining polynomial. TrIm can thus be used to compute mixed fiber polytopes, including ...

Tripartite motif proteins (TRIM) constitute a large family of proteins containing a RING-Bbox-Coiled Coil motif followed by different C-terminal domains. Involved in ubiquitination, TRIM proteins participate in many cellular processes including antiviral immunity. The TRIM family is ancient and has been greatly diversified in vertebrates and especially in fish. We analyzed the complete sets of ...

Due to their ability to hover and to fly “low and slow” VTOL UAVs are of extreme strategic importance. The task of control of VTOL UAVs is however complicated as they exhibit highly coupled nonlinear dynamics and inherent instability. These intricacies limit the performance of linear control techniques since a single linearized state space model represents only a limited part of the flight enve...

Activated macrophages play an important role in many inflammatory diseases including septic shock and atherosclerosis. However, the molecular mechanisms limiting macrophage activation are not completely understood. Members of the tripartite motif (TRIM) family have recently emerged as important players in innate immunity and antivirus. Here, we systematically analyzed mRNA expressions of repres...

Environmental issues and rising fuel prices necessitate better energy efficiency in all sectors. Shipping industry is a stakeholder in environmental issues. Shipping industry is responsible for approximately 3% of global CO₂ emissions, 14-15% of global NO(X) emissions, and 16% of global SO(X) emissions. Ship trim optimization has gained enormous momentum in recent years being an effective opera...

We present TRIM, an abstract machine capable of executing a subset of the algebraic speci cation language OBJ3. A speci cally designed compiler translates the order sorted conditional equations of an OBJ3 speci cation into TRIM code. The fact that TRIM supports order sorted term rewriting natively di erentiates it from many other abstract term rewriting machines. To obtain more e cient abstract...