Ikeda, M., Ohtsuji, H., Kawai, H., and Kuniyoshi, M. (1971). Brit. J. industr. Med., 28,203-206. Excretion kinetics of urinary metabolites in a patient addicted to trichloroethylene. A male Japanese subject, single, aged 38, who worked at a workshop washing metal parts with trichloroethylene, was admitted to our clinic due to addiction to the solvent. Analyses of urine revealed the presence of ...

Human Exposure Trichloroethylene is a common environmental contaminant at Superfund sites, Department of Defense facilities, and certain manufacturing operations (e.g., aircraft, spacecraft). It has been found at approximately 852 of the 1,416 sites proposed for inclusion on the U.S. Environmental Protection Agency (EPA) National Priorities List. On the basis of data reported to the EPA Toxic R...

In cats the sensitivity of the respiratory tract to stimulation with diethyl ether was studied during nitrous oxide, cyclopropane, halothane and trichloroethylene anaesthesia. Nitrous oxide caused little change in sensitivity; halothane and trichloroethylene caused a gradually decreasing sensitivity; and cyclopropane depressed the response only in deep anaesthesia. In addition, following stimul...

This study investigated the human health risks of trichloroethylene from Industrial Complex A. The excessive carcinogenic risks for central tendency exposure were 1.40 × 10(?5) for male and female residents in the vicinity of Industrial Complex A. The excessive cancers risk for reasonable maximum exposure were 2.88 × 10(?5) and 1.97 × 10(?5) for males and females, respectively. These values ind...

Chlorinated solvents and their natural transformation products are the most frequently observed groundwater contaminants in the United States. In situ bioremediation using anaerobic or aerobic co-metabolic processes is a promising means of cleaning up contaminated aquifers. Studies show that under natural conditions trichloroethylene can be anaerobically degraded to dichloroethylene, vinyl chlo...

OBJECTIVES To extend the follow up of a cohort of 14,457 aircraft maintenance workers to the end of 1990 to evaluate cancer risks from potential exposure to trichloroethylene and other chemicals. METHODS The cohort comprised civilians employed for at least one year between 1952 and 1956, of whom 5727 had died by 31 December 1990. Analyses compared the mortality of the cohort with the general ...