1,3,5-Triazines substituted with mono-, di, and tri-[4-(2-chloroethyl)piperazin-l-yl] groups gave products of substitution of chlorine atom when treated with ethanol, phenol, butylamine, toluidine,or thiophenol under mild reaction conditions.

Inverse electron demand Diels-Alder reaction of functionalized 5,5'-bi-1,2,4- triazines with bicyclo[2.2.1]hepta-2,5-diene in boiling p-cymene leads to a range of 6,6'- disubstituted-2,2'-bipyridines in good yield.

The catabolism of chlorinated s-triazines, e.g., herbicides, is incompletely understood. The first demonstration of their quantitative microbial degradation is the fungal dealkylation of simazine (CEET [for meaning of abbreviations throughout, see Table 1, footnote a]) to two major products, deethylsimazine (CEAT; two-thirds of total) and an unidentified s-triazine (one-third of total) (11, 12)...

Recently, the subject was taken up by the first author, who confirmed the results about Simetone (VAN STEEKELENBURG, 1961) and extended them. The results described in the following sections are based upon this recent work. The substituted ureas and the symmetrical triazines are two special and important groups of herbicides. These compounds are taken up by the roots, transported via the xylem a...

This paper is based on the neural folding architecture (FA). The FA is a recurrent neural network architecture which is especially suited for adaptive structure processing, i.e. learning approximations of mappings from symbolic term structures to IR n. The main objective of this paper is to demonstrate that the FA can be successfully applied to approximate quantitative structure activity relati...

In this paper we present the convenient syntheses of seven new phenyl hydrazin derivatives 8 (a-h). For this purpose, acenaphtho [1,2-e]-1,2,4-triazine-9(8H)-thione (3) was prepared, starting from acenaphthylene-1, 2-dione (1) and thiosemicabazide in good yield. The reaction of (3) with benzyl chloride resulted to synthesis of 9-(benzylthio)-acenaphtho[1,2-e]-1,2,4-triazines (5) that reacted wi...

Competition chemiluminescent immunoassay was used in a combination with a neural network (NN) to identify and estimate amounts of three cross-reacting s-triazines (atrazine, terbythylazine and ametryn). Antibodies with different cross-reactivity towards s-triazines were immobilized in separate wells of 8-well microtitre strip or in separate spots of a single membrane strip. The data obtained wi...

Tradescantia 4430 clone stamen hair mutation (Trad-SHM) bioassay was used to evaluate the genotoxicity of a herbicide composed of triazines (atrazine and simazine) after in situ exposure. Thirty plant pots were exposed during the herbicide application (test group) and a control group was maintained in a greenhouse (control group). Genotoxicity was expressed in terms of pink mutation events (EMP...