in western countries such as united states data from 2002-2006 showed that at least 1.7 million people sustain a traumatic brain injury (tbi) each year. of those individuals, about 52,000 die, 275,000 are hospitalized, and 1.365 million are treated and released from an emergency department. in 2000, direct medical costs and indirect costs such as lost productivity of totaled an estimated $76.5 ...

traumatic brain injury (tbi) is one of the serious neurodisorders commonly caused by car accidents and sports. preventive measures are highly recommended to reduce the risk and number of tbi cases. after tbi, the primary injury to the brain initiates a secondary injury process that spreads via multiple molecular mechanisms in the pathogenesis of tbi. many studies in animals using cdna microarra...

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syringobulbiais very rare condition defined as slit-like fluid cavity in the brain stem. several conditions have been reported to be associated with syringobulbia including neoplasms, spinal cord traumas or lesions such as tethered cord, hind-brain herniation, infections such as meningitis and in isolation.although post-traumatic syringomyelia has been wieldy described previously, traumatic bra...

objective(s):estrogen (e2) has neuroprotective effects on blood-brain-barrier (bbb) after traumatic brain injury (tbi). in order to investigate the roles of estrogen receptors (ers) in these effects, er-α antagonist (mpp) and, er-β antagonist (phtpp), or non-selective estrogen receptors antagonist (ici 182780) were administered. materials and methods: ovariectomized rats were divided into 10 gr...

conclusions mild traumatic brain injuries despite of the normal ct scan and history of substance abuse are closely related to psychological symptoms. therefore, it is recommended that patients with brain trauma 6 months post-injury and subjects with a history of substance abuse be evaluated for psychological distress to support better rehabilitation. background it is well-known that severe brai...