We aimed to model esophageal bolus transit based on esophageal pressure topography (EPT) landmarks, concurrent intrabolus pressure (IBP), and esophageal diameter as defined with fluoroscopy. Ten healthy subjects were studied with high-resolution impedance manometry and videofluoroscopy. Data from four 5-ml barium swallows (2 upright, 2 supine) in each subject were analyzed. EPT landmarks were u...

introduction: renal dynamic study is a well-established and popular test in routine practice of nuclear medicine. the test is non-invasive, rapid and unique in evaluation of the kidney function. in despite of its clinical values, the parameters derived from renogram are physiologically meaningless. that is due to the fact that renogram is not the true kidney function. from mathematical points o...

[1] Subsurface flow from hillslopes is widely recognized as an important contributor to streamflow generation; however, processes that control how and when hillslopes connect to streams remain unclear. We investigated stream and hillslope runoff dynamics through a wet‐up period in watershed 10 of the H. J. Andrews Experimental Forest in the western Cascades of Oregon where the riparian zone has...

Stem cells reside in specialized niches that regulate their self-renewal and differentiation. The vasculature is emerging as an important component of stem cell niches. Here, we show that the adult subventricular zone (SVZ) neural stem cell niche contains an extensive planar vascular plexus that has specialized properties. Dividing stem cells and their transit-amplifying progeny are tightly app...

Neural stem cells in the subventricular zone (SVZ) continue to generate new neurons in the adult brain. SVZ cells exposed to EGF in culture grow to form neurospheres that are multipotent and self-renewing. We show here that the majority of these EGF-responsive cells are not derived from relatively quiescent stem cells in vivo, but from the highly mitotic, Dlx2(+), transit-amplifying C cells. Wh...

We analyze a sample of multiple-exoplanet systems which contain at least 3 transiting planets detected by the Kepler mission (‘Kepler multiples’). We use a generalized Titius-Bode relation to predict the periods of 228 additional planets in 151 of these Kepler multiples. These Titius-Bode-based predictions suggest that there are, on average, 2± 1 planets in the habitable zone of each star. We e...

I discuss the possibility that white dwarfs might harbor habitable planets at 0.01 AU that arrive there after the red giant phase. These planets would be detectable with ground-based telescopes via deep transits of the star, and a transit survey of the nearest white dwarfs would favor detection of Earth-temperature planets, assuming they could form as close as twice the Roche limit. I show that...