نتایج جستجو برای: transforming growth factor beta 1
تعداد نتایج: 3961439 فیلتر نتایج به سال:
BACKGROUND Regulatory T cells have been suggested to have a protective role against acute rejection in allograft recipients. However, there is little information available about their contribution to chronic rejection process. The role of transforming growth factor-beta 1 (TGF-β1) as a profibrogenic and/or immunoregulatory cytokine in renal allografts is also controversial. OBJECTIVES To eval...
The expression of transforming growth factor-beta 1 (TGF-β1) inside the callus cells of diabetic rats and the impact of insulin therapy on its expression and biomechanics was investigated. The rats were randomly divided as follows: an insulin therapy group (IT), a diabetic model group (DM), and a non-diabetic control group (NC). Bone specimens from each group were extracted at different times f...
Transforming growth factor beta (TGF-beta) induces apoptosis in a variety of cells. We have previously shown that TGF-beta 1 rapidly induces apoptosis in the FaO rat hepatoma cell line. We have now studied the effect of TGF-beta 1 on the expression of different members of the Bcl-2 family in these cells. We observed no detectable changes in the steady-state levels of Bcl-2, Bcl-X(L), and Bax. H...
BACKGROUND AND PURPOSE The aim of this study was to examine the effect of transforming growth factor-beta 1, a cytokine shown to amelioriate cardiac ischemia, in a rabbit model of thromboembolic stroke. METHODS An autologous clot embolus was introduced intracranially through the right internal carotid artery in 21 New Zealand White rabbits, with seven in each group receiving either vehicle co...
background and objectives: nasal polyposis is a diseases resulting from complex pathogenetic mechanisms. some studies showed that tgfβ1 had significant role in this pathogenesis. in this study, we investigated the roe of cytokines and mediators in polyp development. material and methods: in this case- control study, healthy nasal mucosal samples were obtained from 24 people undergoing septoplas...
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