نتایج جستجو برای: transcriptional targeting

تعداد نتایج: 260708  

2017
Bita Javan Majid Shahbazi

Transcriptional targeting is the best approach for specific gene therapy. Hypoxia is a common feature of the tumour microenvironment. Therefore, targeting gene expression in hypoxic cells by placing transgene under the control of a hypoxia-responsive promoter can be a good strategy for cancer-specific gene therapy. The hypoxia-inducible gene expression system has been investigated more in suici...

Journal: :Plant biotechnology journal 2015
Agnieszka Piatek Zahir Ali Hatoon Baazim Lixin Li Aala Abulfaraj Sahar Al-Shareef Mustapha Aouida Magdy M Mahfouz

Targeted genomic regulation is a powerful approach to accelerate trait discovery and development in agricultural biotechnology. Bacteria and archaea use clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) regulatory systems for adaptive molecular immunity against foreign nucleic acids introduced by invading phages and conjugative plasmids. The type II...

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