According to the current European Association for the Study of Liver guidelines, transarterial chemoembolization (TACE) is the recommended first-line therapy for patients with intermediate-stage (Barcelona Clinic Liver Cancer-B class) hepatocellular carcinoma (HCC). The efficacy of this therapy is supported by robust evidence; however, there is still a lack of standardization in treatment metho...

Metastasis of hepatocellular carcinoma (HCC) to the ovary is notably rare. We present a case of HCC metastasis to the ovary with a review of the literature, which includes only 7 reported cases. A 43-year-old hepatitis B virus carrier was admitted with a right ovarian cystic mass. She had been diagnosed with HCC 2 years prior, for which she underwent transarterial chemoembolization followed by ...

BACKGROUND We evaluated treatment modalities and survival in patients with hepatocellular carcinoma (HCC), by pre-treatment and 3-month post-treatment serum alpha-fetoprotein (AFP) levels and pre-treatment tumor diameters. METHODS We retrospectively reviewed 57 patients treated for HCC in our department from January 2002 to December 2012, including their sex, type of hepatitis, Child class, p...

BOGDAN VALERIU POPA1#, ANA MAGDALENA BRATU2#, COSTIN AURELIAN MINOIU2*#, CLAUDIU TURCULET1#, DRAGOS ENE1#, GABRIEL CONSTANTINESCU1#, MADALINA ILIE1#, MIHAI POPESCU3#, ELISABETA BADILA1# 1 Clinical Emergency Hospital, 8 Floreasca Rd., 014461, Bucharest, Romania 2 Clinical Hospital “Coltea” Bucharest, 1 I.C. Bratianu Str., 030171, Bucharest, Romania 3 UMF Craiova Emergency Hospital, 54 Matei Mill...

BACKGROUND Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most common cause of cancer-related deaths. Hepatic resection and liver transplantation are considered to be the preferred treatment for HCC. However, as novel therapeutic options such as image-guided locoregional therapies have emerged and been refined, the manner in which HCC is treated has chang...

UNLABELLED INTRODUCTION Doege-Potter syndrome is a paraneoplastic syndrome characterized by non-islet cell tumor hypoglycemia secondary to a solitary fibrous tumor. This tumor causes hypoglycemia by the secretion of a prohormone form of insulin-like growth factor II. We describe the diagnosis and management of Doege-Potter syndrome and the use of transarterial chemoembolization in a patient ...

Amongst therapies for unresectable hepatocellular carcinomas, radiofrequency ablation (RFA) and hepatic artery chemoembolization have clinical application either for local tumor destruction or to control tumor progression and recurrence rate. Herein we present a patient with a large hepatocellular carcinoma, chronic hepatitis B and congenital absence of left hepatic lobe treated with hepatic ar...

The potential for increased efficacy with combined transarterial chemoembolization and sorafenib is a topic of increased interest to specialists who care for patients with unresectable hepatocellular carcinoma. There is strong scientific rationale for combination therapy: transarterial chemoembolization produces ischemia and stimulates hypoxia-inducible factor-1α, resulting in a local and syste...

At an intermediate or advanced stage, i.e. stage B or C, based on the Barcelona Clinic Liver Cancer classification of hepatocellular carcinoma (HCC), transarterial chemoembolization (TACE) may be offered as a treatment of palliative intent. We report the case of a patient suffering from acute respiratory distress syndrome after TACE with drug-eluting beads loaded with doxorubicin for HCC. To ou...