This paper describes a novel and efficient analytical method to define the profile of fat-soluble micronutrients in milk from different animal species. Overnight cold saponification was optimized as a simultaneous extraction procedure. Analytes were separated by nonaqueous reversed-phase (NARP) chromatography: carotenoids on a C(30) column and fat-soluble vitamins on a tandem C(18) column syste...

periodontitis (pd) is known to be one of most prevalent worldwide chronic inflammatory diseases. there are several treatments including antibiotics for pd; however, since drug resistance is an increasing problem, new drugs particularly derived from plants with fewer side effects are required. the effects of trans-anethole on il-1 β and tnf-α level in a rat model of pd were investigated and comp...

The amyloid precursor protein (APP) plays a central role in Alzheimer's disease (AD) and has essential synapse promoting functions. Synaptogenic activity as well as cell adhesion properties of APP presumably depend on trans-cellular dimerization via its extracellular domain. Since neuronal APP is extensively processed by secretases, it raises the question if APP shedding affects its cell adhesi...

Frankincense is an oleo-gum-resin collected from wild Boswellia spp. trees, and widely used in perfumery, cosmetics, aromatherapy, incense, other industries. rivae, growing Ethiopia, Somalia, Kenya, one source of frankincense, but little-commercialized compared to species such as B. sacra, frereana, papyrifera. In this study, we examine the resin essential oil chemistry harvesting systems rivae...

A new chiral iron porphyrin-based catalyst performed α-methylstyrene stereoselective cyclopropanation with excellent yields (up to 99%), enantio- and diastereoselectivities (ee(trans) up to 87%, trans/cis ratios up to 99 : 1) and outstanding TON and TOF values (up to 20,000 and 120,000 h(-1) respectively).

An unprecedented Pd-catalyzed trans-addition of boronic acids to ynamides has been reported, giving α,β-disubstituted enamides in high yields with excellent regio- and stereoselectivity. A possible mechanism involving the palladium carbene intermediate has been proposed to account for the unusual trans-addition.

L. stoechas subsp. luisieri is one of the five spontaneous species genus Lavandula that occurs spontaneously in Portugal. The chemical profile and antifungal activity essential oils were investigated. oil two phenological stages was isolated by hydrodistillation their components analyzed GC-FID/GC-MS. minimum inhibitory concentration (MIC) fungicidal (MFC) both determinate to verify against dif...

Proline derivatives with a C(γ)-exo pucker typically display a high amide bond trans/cis (K(T/C)) ratio. This pucker enhances n→π* overlap of the amide oxygen and ester carbonyl carbon, which favors a trans amide bond. If there were no difference in n→π* interaction between the ring puckers, then the correlation between ring pucker and K(T/C) might be broken. To explore this possibility, prolin...

The primary conjugated linoleic acid (CLA) isomer in milkfat, cis-9, trans-11 CLA, is a proven anticarcinogen in rodents and can be derived directly from ruminal biohydrogenation of linoleic acid. The major fatty acid in pasture, however, is α–linolenic acid; the biohydrogenation of which does not produce cis-9, trans-11 CLA as an intermediate. Therefore, in grazing cows, cis-9, trans-11 CLA mu...