Background: Functional gastrointestinal diseases are common in general populations and comprise more than 40% visits to gastroenterologists. Treatment options of gastrointestinal diseases have been limited. There are a few medications for functional gastrointestinal diseases and some of medications are not available in the market or in the place where the patient lives. Traditional Persian medi...

BACKGROUND Traditional Persian medicine (TPM) is based on humors theory. Temperament or mizaj is the result of a combination of four fundamental humors called blood, phlegm, yellow bile, and black bile. Like any other diseases, acne is the result of humoral imbalance. Acne is a highly prevalent dermatological problem, which has both physical and psychological effects on patients. The aim of thi...

Background and objectives: Ruscus genus from Asparagaceae (popularly called Butcher`s broom) are perennial rhizomatous evergreen herbs and grows in Europe and south western Asia. They are generally used as anti-inflammatory, diaphoretic, diuretic, mildly laxative, and vasoconstrictive agents in many countries. Ruscus hyrcanus Woronov is widely distributed in n...

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Objective: As a rare autoimmune disease, pemphigus vulgaris has a poor prognosis especially in lack of proper medical support. This blistering disease involves both the skin and mucus membranes. The challenge is improving the healing process of skin lesions of which, superimposed infections are among the main causes of the disease mortality. Accordingly, we aimed to assess the treatment options...

Plantago major has been used widely since ancient times, to manage a wide range of diseases including constipation, coughs and wounds. The aim of this study is to review the traditional application, botanical characterization, pharmacological activities, phytochemistry effects and toxicity of Plantago major. In this review study, medicinal properties of Plantago major are collected from credibl...

BACKGROUND Cancer is the most important non-communicable disease and the chief cause of death in the world, which imposes a major burden on communities. It is expected that the number of new cancer cases will increase 70 percent worldwide in the next two decades. The exact cause of the disease is unclear in modern medicine. More than a third of all cancer cases are preventable and the other two...

Comprehensive explanation about milk oversupply is not available in the current literature because few studies have been done on this topic. In traditional Persian medicine, milk oversupply and its management have been described. The aim of this study was to investigate milk oversupply from the perspective of medieval Persian practitioners. In this study, some main medical resources of traditio...

using nigella sativa l. (black cumin), in traditional medicine, dates back to tutankhamen, the pharaoh of egypt. there are aboundant historical and religious evidence implying the importance of these curative seeds. traditionally, they have been used for various therapeutic purposes. zokam and nazleh (zan) are two nasal diseases used to be treated by these medicinal seeds. traditional persian m...

background and purpose: cutaneous leishmaniasis (cl) is caused by infection with leishmania parasites. standard treatment of cl includes pentavalent antimonials that are currently used in severe cases due to prolonged systemic therapy, high toxicity, complications, low efficacy, and resistance against the drug. therefore, it is necessary to develop new drugs or combination therapy for treatment...