Toxoplasma infect ion is c o m m o n in m a n and animals, ye t for 60 years the life cycle of Toxoplasma gondii remained unknown. Recen t ly a new form of Toxoplasma was found in the feces of cats t ha t had ea ten Toxoplasma-infected mice (for rev iew of earlier work see [1]). Th is fecal form is biological ly different f rom the known stages of Toxoplasma. While searching the feces of cats f...

Toxoplasma gondii is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission to the fetus. However it is not certain whether Toxoplasma infection can cause recurrent abortion. The aim of this study was to determine the relationship between To...

Pathogen-host protein-protein interaction systems examine the interactions between the protein repertoires of 2 distinct organisms. Some of these pathogen proteins interact with the host protein system and may manipulate it for their own advantages. In this work, we designed an R script by concatenating 2 functions called rowDM and rowCVmed to infer pathogen-host interaction using previously re...

Numerous recent studies show that vitamin D deficiency potentiates various chronic physical and psychiatric disorders diseases. It has been shown a similar range of is also associated with latent infection Toxoplasma gondii (Nicolle et Manceaux, 1908). For instance, among cancer, diabetes schizophrenia patients, we find higher prevalence both toxoplasmosis deficiency. Theoretically, therefore, ...

Toxoplasma infect ion is c o m m o n in m a n and animals, ye t for 60 years the life cycle of Toxoplasma gondii remained unknown. Recen t ly a new form of Toxoplasma was found in the feces of cats t ha t had ea ten Toxoplasma-infected mice (for rev iew of earlier work see [1]). Th is fecal form is biological ly different f rom the known stages of Toxoplasma. While searching the feces of cats f...

Swine toxoplasmosis is one of the most important diseases of pigs in Japan. Toxoplasma is a causal agent of zoonoses infecting not only swine, but also many kinds of mammals, including man. Therefore, routes of infection have been examined in toxoplasmosis of man and animals. Congenital transmission has already been confirmed in man and animals, but no acquired infection has been fully understo...

Coccidian oocysts resembling those of Isospora bigemina were excreted by cats fed Toxoplasma. In order to identify these oocysts with Toxoplasma infectivity a number of critical comparisons were made. The appearance of oocysts and Toxoplasma infectivity was simultaneous in the feces of 23 of 24 adult cats, 3-5 days after feeding of Toxoplasma cysts; in the feces of 4 out of 9 cats, 7-10 days af...

PURPOSE To evaluate the effects of drug therapy on the clinical course of acute acquired Toxoplasma retinochoroiditis and on the number of Toxoplasma cysts present in the brain and ocular tissues in the hamster animal model. METHODS The Syrian golden hamster animal model of Toxoplasma retinochoroiditis was used. In acute disease, systemically administered atovaquone was compared with conventi...

Toxoplasma gondii, an obligate intracellular protozoan parasite, is one of the most successful eukaryotic pathogens. It can infect virtually any warm-blooded animal, including humans, in whom it can cause serious disease. Its success is likely due to its ability to modulate host immune responses and host innate immune signaling pathways allowing it to establish a chronic infection with few symp...