CONTEXT FNAC thyroid is more sensitive as well as specific in segregating neoplastic and non-neoplastic thyroid lesions. Identification of predominant cell pattern, cell morphology and background details in FNAC smears play an important role in categorisation of various thyroid lesions with accuracy. Marginal vacuoles (MVs) have been described as irregular cytoplasmic vacuoles with largely unst...

Aim: Thyroid fine needle aspiration biopsy (FNAB) performed with ultrasonography is an effective method in diagnosing thyroid cancer. Nevertheless, some of them have non-diagnostic results. The aim to investigate the factors that affect result.
 Material and Method: FNABs 361 nodules patients were analyzed retrospectively. divided into two groups as result without non-diagnostic. compared ...

Both Graves' disease and Toxic Nodules cause thyrotoxicosis, albeit by different mechanisms. Their coexistence is called Marine-Lenhart syndrome, the prevalence of which has been reported 2.7-4.1%. In many cases with Marine Lenhart syndrome Graves' disease is accompanied by multiple hyperfunctioning nodules, although it is accompanied by a solitary hyperfunctioning nodule in rare cases. We here...

the nodular thyroid diseas is one of the most common disturbances o the thyroid gland wheras malignant tumors are among the most unusual entities of it. not only differentiation of these two spectra but also the problems to achieve early diagnosis and treatment, have been a matter of concern, research, and controversy. two hundred patients were assessed at the cancer institute of imam khomeini ...

INTRODUCTION Measuring thyroid stimulating hormone levels alone may be insufficient to appropriately evaluate thyroid function. Reduced thyroid stimulating hormone levels associated to normal/reduced FT4 levels should prompt investigation of pituitary function, on suspicion of hypopituitarism. Pituitary macroadenomas are the most common cause of hypopituitarism; among these, macroprolactinomas ...

Toxic thyroid adenoma presenting as hypokalemic periodic paralysis is extraordinarily rare. We describe a 26-year-old Japanese man who suffered from acute and painful muscle weakness of extremity in the morning. Physical examination showed a left anterior neck mass and laboratory tests revealed hypokalemia during his paralysis, and thyrotoxicosis. Neck sonogram showed a solitary nodule in the l...

Thyrotropin (TSH) is the prime regulator of thyroid cell growth and function and acts through the thyrotropin receptor (TSHR) located on the surface membrane of thyrocytes. Somatic heterozygous mutations that cause TSHR activation in the absence of TSH have been found in toxic adenomas and in hot nodules of multinodular goiters. Clinically and histologically heterogeneous nodules can share comm...

UNLABELLED This study aimed to determine the reference range of 24-h radioiodine uptake in euthyroid Jordanians, as well as the reference ranges for patients with diffuse and nodular hyperthyroidism. In addition, radioiodine uptake ranges were determined for those patients with Hashimoto's thyroiditis and early-phase subacute thyroiditis. METHODS The medical records of 285 Jordanian patients ...

OBJECTIVES This retrospective study was aimed at evaluating the efficacy of radioiodine (RI) treatment for patients with autonomously functioning thyroid nodules (AFTN). METHODS The subjects were 38 patients including 26 cases of toxic adenoma (TA) and 12 cases of toxic multinodular goiter (TMNG), who attended our clinic from July 1999 to April 2005. RI treatment was performed in the outpatie...