background: suicide is a problem worldwide and occupation is an important risk factor. in the last decade, 55 200 deaths in the us were attributed to occupational risk factors. objective: to determine if toxic metal exposure was associated with suicide risk among paducah gaseous diffusion plant (pgdp) workers. methods: we assembled a cohort of 6820 nuclear industry workers employed from 1952 to...

This paper examines the effect of reporting thresholds on the use of TRI data for both time-series and cross-sectional policy analysis. Facilities are only required to report releases to TRI if their use of a chemical exceeds some threshold. This creates an incentive for facilities to reduce their use of a listed chemical to a level just below the reporting threshold. However, this does not nec...

In this research, gelatin nanoparticles were synthesized via inverse miniemulsion method by employing a mixture of a water soluble carbodiimide (CDI) and N-hydroxysuccinimide (NHS) as a non-toxic cross-linking system. The gelatin nanoparticles were characterized for their size and size distribution, morphology and stability and were compared with those of nanoparticles cross-linked by glutarald...

diabetes mellitus (dm) is a metabolic disorder resulting from a defect in insulin secretion, insulin action or both. despite the fact that it has a worldwide high prevalence, morbidity and mortality, it is regarded as a non–curable but controllable disease. in addition to different synthetic drugs, plant remedies and dietary traditions play an effective role in treatment. teucrium polium l. is ...

Cyclodisone is an active alkylating antitumor agent that is being considered for Phase 1 clinical trials in humans and is currently undergoing toxicological evaluation. Cyclodisone was found to be more toxic to human colon carcinoma cells of the Mer- phenotype (BE) than cells of the Mer+ phenotype (HT-29). DNA interstrand cross-links were observed in the sensitive cell line but only at concentr...

This paper shows that citric acid can cross-link starch and improve the tensile strength, thermal stability and decrease the dissolution of starch films in water and formic acid. The poor mechanical properties and water stability of starch have restricted its industrial applications. Although cross-linking is a common approach to improve the properties of starch products, current starch cross-l...

septic arthritis with polyarticular presentation is an uncommon clinical entity. a case of complicated staphylococcal infection with purulent and reactive polyarthritis, osteomyelitis, cutaneous and pleuropericardial involvement as well as transient blindness is presented here.

toxic shock syndrome in children following infection with influenza is a very rare syndrome. if it is not diagnosed quickly, it may cause significant morbidity and mortality. for diagnosis of toxic shock syndrome, clinical and laboratory criteria are used. our patient is a 3.5-year old boy who admitted to the hospital with high fever, weakness, toxicity, hypotension and skin rash due to influen...

toxic optic neuropathy (ton) is a group of medical disorders which can be defined by visual impairment due to optic nerve damage by a toxin. the exposure to a toxic substance can occur at the workplace, with ingestion of materials/ foods containing a toxin, or the use of systemic medications. ton is a disease entity which is not only under-diagnosed, but also often diagnosed at a stage when rec...

conclusions the nps-induced ots may increase the pro-inflammatory responses. on the other hand, administration of antioxidants such as nac and vitamin c and e prior to exposure to metal nps significantly decreases ots conditions. evidence acquisition here, a nanotechnology approach is evaluated using nps in human neuronal protection against ots. it may be wide therapeutic applications in the ca...