Background: Considering the increasing rates of early hospital discharge and kernicterus in healthy full term newborns, timely identification of neonates at risk of severe hyperbilirubinemia is of great significance. The aim of this study was to investigate the predictive value of umbilical cord serum (UCS) bilirubin level for subsequent hyperbilirubinemia. Moreover, we compared the predictive ...

Background: Hyperbilirubinemiais a common problem in newborn infants. It can progress to kernicterus in severe forms, unless an intervention is initiated. The objective of this study was to compare the efficacy of Clofibrate with Phenobarbital in full-term neonates with nonhemolytic jaundice. Methods: this double blind clinical trial study was performed on 60 neonate who were divided randomly i...

  Abstract   Background: Regarding the diagnostic errors of the classic criteria including serum ascites   albumin gradient (SAAG), total protein concentration and the adapted Light et al’s criteria   in distinguishing transudate versus exudates, we evaluated the ascitic fluid to serum   bilirubin ratio as a new criteria in this regard. We also evaluated whether the combination of   bilirubin r...

BACKGROUND Gilbert's syndrome (GS) is the most common inherited disorder of bilirubin metabolism. Recent data show that the rifampin test can be used as a diagnostic test but there is controversy about its effect on bilirubin level in normal individuals. We studied the effect of administration of rifampin on serum bilirubin level in patients with GS and in healthy individuals. METHODS Serum t...

OBJECTIVE To evaluate the use of a point-of-care transcutaneous bilirubinometer, JM-103 Minolta, for estimation of the serum bilirubin level in the management of neonatal jaundice in term or near-term Chinese neonates. DESIGN Prospective correlation study. SETTING Accident and Emergency Department of a regional hospital in Hong Kong. PATIENTS All term or near-term Chinese neonates aged 3 ...

ROPER CLINICAL MANAGEMENT of infants with erythroblastosis fetalis necessitates the determination of total serum bilirubin. Of the many modifications of the original diazo reaction on blood serum (1) a micromethod using capillary blood is preferable. One tenth miffiliter of serum was used by Davidson et al. (2) in their modification of the Ernst and F#{246}rster (3) method and by With (4, 5) in...

The absorbance at 450 mJ.Lof serum diluted with acidified ethylene glycol is used as a measure of the serum’s total bilirubin content in a single-tube, single-extraction method for rapid determination of free and total bilirubin in 0.1 ml. of serum. With the addition of chloroform, free bilirubin is extracted into the chloroform but conjugated bilirubin remains in the ethylene glycol. Free bili...

The apparent body clearance of chloramphenicol was investigated in 21 hospitalized adult patients on 27 occasions. Apparent body clearance was found to be significantly lower (1.99 +/- 1.49 ml/min per kg) in patients with total serum bilirubin concentrations of >1.5 mg/100 ml than in patients with serum bilirubin concentrations of </=1.5 mg/100 ml (3.57 +/- 1.72 ml/min per kg; P < 0.001). Serum...