Most of the floating systems have an inherent drawback of high variability in the GI transit time, invariably affecting the bioavailability of drug. An attempt has been made to develop floating drug delivery system for improving the drug bioavailability by prolongation of gastric residence time of famotidine in stomach. The floating microballoons were prepared using polymer Eudragit L-100 by so...

Atenolol, an antihypertensive drug, has poor bioavailability (40-50%) and has has low elimination half life(6 hr). Atenolol is mainly absorbed in the stomach. The floating tablets of atenolol were prepared to increase the gastric retention, extend the drug release and to improve the bioavailability of the drug. The floating tablets were formulated using HPMC 100 cps, sodium alginate, carbopol 9...

The present investigation deals with the optimization, formulation, and characterization of oral in situ gel of spiramycin. Sodium alginate and hydroxypropyl methylcellulose were used as cross-linking and viscosifying agents, respectively. Sodium bicarbonate was used as a floating agent. In preformulation studies, the melting point, pH, and partition coefficient were found to be 133 °C, 9.5, an...

Floating-point arithmetic is considered an esoteric subject by many people. This is rather surprising because floating-point is ubiquitous in computer systems. Almost every language has a floating-point datatype; computers from PCs to supercomputers have floating-point accelerators; most compilers will be called upon to compile floating-point algorithms from time to time; and virtually every op...

determining the responses of floating structures at sea are the most important concerns in shipbuilding industry. in physical and dynamical principles a ship can be analyzed as a free elastic beam floating in sea without any supports. the analysis of corresponding dynamic equations are difficult and time- consuming, thus investigation on the behavior of floating structures can be done numerical...

Gastrointestinal disturbances, such as nausea and vomiting, are considered amongst the main adverse effects associated with oral anticancer drugs due to their fast release in the gastrointestinal tract (GIT). Sustained release formulations with proper release profiles can overcome some side effects of conventional formulations. The current study was designed to prepare sustained release tablets...

This paper is to evaluate and compare some of the fundamental metrics for selected ALU designs, covering both time and space complexity. The references examined consists of papers from 1999 to present. A total of ten different designs on ALU and Floating points are examined and compared. Some of the key components evaluated are clock rate, memory capacity, components, floating point, ALU, FPGA,...

Rapid Serial Visual Presentation (RSVP) is an effective tool for information navigation. We applied RSVP to the increasingly important task of image browsing. In total nine RSVP interfaces were developed, implementing three RSVP modes and three control sets. An evaluation was carried out to investigate the effect of RSVP mode and control set on image retrieval time. Subjective measures were als...