Abstract Background Self-emulsifying system-based lipstick may prove to have the potential of enhancing moisturizing characteristics and delivering hydrophobic drug antifungal drugs for management lip fungal infection, especially candidiasis. In this study, self-emulsifying delivery system (SEDDs) ketoconazole was obtained using IPM (Oil), Tween 80 (surfactant), PEG 400 (co-surfactant). The med...

Objective: Leishmania recidivans is a chronic form of cutaneous leishmaniasis with characteristic picture. So the aim this study to record all cases leishmania that had history therapy by sodium stibogluconate. Patients and methods: This case series descriptive interventional therapeutic. Twenty-two patients clinical picture were included. All gave 2-4-month duration before time therapeutic inj...

BACKGROUND A number of effective topical therapies are available for the treatment of tinea versicolor (TV). However, topical antifungals are difficult to apply to a large body surface area and for this reason TV is perhaps more easily treated with systemic agents. METHODS A total of 128 patients with TV, aged 15-55 years, were entered into a randomized, double-blind, clinical trial comparing...

The study was conducted on 48 clinical cases of dogs with the objective of recording clinical signs, identifying etiological agents and therapeutic management of otitis in dogs. Various clinical signs of otitis were aural pruritus , ear pain, foul odour of ear discharge, head tilt, erythema of pinna, alopacia ,scaling, crusting of pinna and swelling at the base of the ear canal. Otoscopic exami...

BACKGROUND Fungal keratitis is one of the major causes of infectious keratitis in tropical countries. Symptoms of fungal keratitis consist of blurred vision, redness, tearing, photophobia, pain and foreign body sensation. If not treated effectively, it could lead to blindness. Common causes include Candida spp., Fusarium spp. and Aspergillus spp.. With the limited choices of topical antifungal ...

Fungal infections have emerged as a world-wide health care problem in recent years, owing to the extensive use of broad-spectrum antibiotics. We screened 104 pregnant women with symptoms of vaginal candidiasis in the antenatal clinic of Thika District Hospital, Kenya in order to identify vaginal Candida species and determine their susceptibility profile to commonly used antifungal drugs for tre...

Background and Purpose: Trichophyton quinckeanum, a known zoophilic dermatophyte responsible for favus form in rodents camels, is occasionally reported to cause human infections. Case Report: This study aimed report case of tinea corporis caused by T. quinckeanum that experienced annular erythematous pruritic plaque with abundant purulent secretions. In June 2021, 15-year-old girl an cup shape ...

The in vitro activity of R 51,211 (itraconazole, accepted generic name; Janssen Pharmaceutica, Beerse, Belgium), a new orally active triazole, was compared with those of two existing orally active azoles, ketoconazole and BAY n 7133, and a topical agent, Ro 14-4767/002. An agar dilution procedure (Kimmig agar) was performed with 148 isolates of pathogenic fungi. Incubation was at 30 degrees C f...

We present the results of studies of the in vitro susceptibility of 52 isolates of Trichophyton rubrum and 40 of Trichophyton mentagrophytes to griseofulvin, terbinafine, itraconazole, ketoconazole, fluconazole and cyclopiroxolamine. All test strains were recovered from patients with toe nail onychomycosis and the minimum inhibitory concentration (MIC) of each antifungal against both species wa...