PURPOSE To compare the clinical efficacy between locally applied diclofenac diethylamine gel, EMLA cream and systemically given diclofenac sodium for the pain relief during extracorporeal shock wave lithotripsy (SWL) using Dornier Delta Compact Lithotripter. MATERIAL AND METHODS One hundred five patients with renal stones were randomly divided in to 3 groups. Group A was given intramuscular d...

Epsom salt as Osteoarthritis (OA) pain therapy has been limited to compresses, foot soaks, and baths. Many studies have examined reduce pain, especially in OA, but formulation gel form never tried, so it needs in-depth scientific evidence. This study aims formulate an test its effectiveness reducing for OA patients. is a true-experimental with completely randomized design. A total of 22 respond...

The objective of this article is to review published clinical data on diclofenac epolamine topical patch 1.3% (DETP) in the treatment of acute soft tissue injuries, such as strains, sprains, and contusions. Review of published literature on topical nonsteroidal anti-inflammatory drugs (NSAIDs), diclofenac, and DETP in patients with acute soft tissue injuries was included. Relevant literature wa...

OBJECTIVE The aim of this study was to evaluate the effect of topical treatment with pregabalin and diclofenac on neuropathic orofacial pain induced by infraorbital nerve injury in the rat. STUDY DESIGN Sixty-four Sprague-Dawley rats underwent infraorbital nerve injury. Seven days after surgery, pain was verified and the rats randomly assigned to topical or systemic treatment with pregabalin ...

Actinic keratoses are rough, scaly lesions that commonly occur on sun-exposed areas of the skin. The prevalence of the condition increases with age. Actinic keratoses are thought to be carcinomas in situ, which can progress to squamous cell carcinomas. The decision to treat can be based on cosmetic reasons; symptom relief; or, most importantly, the prevention of malignancy and metastasis. Treat...

Hand foot syndrome (HFS) is a dose-limiting side effect of capecitabine in patients with gastrointestinal (GI) cancer. Celecoxib, an oral cyclo-oxygenase-2 (COX-2) inhibitor effective reducing the incidence associated HFS. However, it has not been adopted clinics due to concerns regarding cardiac and toxicity. We report efficacy topical diclofenac prevention HFS GI cancers. In D-ToRCH (Diclofen...

purpose : to evaluate the effect of topical diclofenac sodium 0.1% on the corneal epithelial healing after photorefractive keratectomy (prk) methods : in this prospective randomized double blind clinical trial, prk was performed on 82 patients. thirty-three cases of them receiving topical diclofenac four times per day after surgical procedure and 45 patients did not receive this medication as a...

AIM To determine if preoperative treatment with a topical non-steroidal anti-inflammatory drug (NSAID) lowers the concentration of intraocular interleukin (IL)-12 and the incidence of postoperative macular edema in patients with non-proliferative diabetic retinopathy undergoing cataract surgery. METHODS A total of 55 patients were randomized to diclofenac (n=27) or placebo (n=28). Patients re...

This randomized controlled trial aimed to investigate the distinctness after treatment among hot herbal compress, hot compress, and topical diclofenac. The registrants were equally divided into groups and received the different treatments including hot herbal compress, hot compress, and topical diclofenac group, which served as the control group. After treatment courses, Visual Analog Scale and...