Tilmicosin (TLM) is an important antibiotic in veterinary medicine with low bioavailability and safety. This study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization and antibacterial activity of three TLM-loaded lipid nanoparticles (TLM-LNPs) including solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs) and lipid-core nanocapsu...

BACKGROUND The optimal treatment method of T1 glottic squamous cell carcinoma (SCC) with involvement of the anterior commissure is still debatable. We compared the outcomes of radiotherapy (RT) and transoral laser microsurgery (TLM). METHODS Data were retrospectively collected for 54 patients who were treated by RT (n = 38) or TLM (n = 16) from 2006 to 2013. RESULTS No between-group differe...

Dual scattering channel (DSC) schemes naturally extend the transmission line matrix (TLM) numerical method beyond the lines set up by P.B. Johns and coworkers. Conceptually, DSC schemes retain from TLM the typical formal splitting of the computed fields into incident and reflected components, interchanged and scattered between adjacent cells, without yet a need for transmission lines. They gene...

Ecological sampling can be labor intensive, and logistically impractical in certain environments. We optimize line intercept sampling and compare estimation methods for assessing feral swine damage within fragile wetland ecosystems in Florida. Sensitive wetland sites, and the swine damage within them, were mapped using GPS technology. Evenly spaced parallel transect lines were simulated across ...

A reformulation of the Transmission Line Matrix (TLM) method is presented to model non-dispersive anisotropic media. Two TLM-based solutions solve this problem can already be found in literature, each one with an interesting feature. One considered a more conceptual approach, close TLM fundamentals, which identifies Maxwell’s equations specific line. But simplicity achieved at expense increase ...

Most traditional theories of speech production are currently based on plane waves and on one-dimensional analysis. It i s however well-known that when the frequency of sound reaches a cut-on frequency, higher acoustical modes start to propagate and can become predominant. It is therefore important to evaluate the effects of these higher modes, especially in order to improve acoustical models of...

The development of a Transmission-Line Matrix (TLM) for the simulation of ultrasound and microwave propagation in structures common in Nondestructive Testing (NDT) is described. The spatial resolution of the proposed model is better than a tenth of a wavelength. Numerical modeling was carried out for frequencies commonly used in ultrasound and microwave nondestructive testing (3.5MHz – 20GHz). ...

BACKGROUND Angiotensin II type 1 receptor (AT1R) blockers have various benefits on hypertension and/or heart failure. We demonstrated that telmisartan (TLM), an AT1R blocker, causes sympathoinhibition by reduction of reactive oxygen species (ROS) in the rostral ventrolateral medulla (RVLM) of stroke-prone spontaneously hypertensive rats (SHRSPs). The aim of this study was to determine whether T...