A simple, sensitive, rapid, reproducible, economical and easily accessible method for the determination of tinidazole tablets is described. From the experiment carried out there is the need for recrystallisation of tinidazole tablet before it is analysized. Ultraviolet (UV) absorption analysis corresponds to the result obtained with non-aqueous titration. And the best solvent to be use for non-...

The isohydricity (pH constancy) as the property referred to mixtures of acids or bases, is illustrated on a simple example of the solutions: HL (C0, mol/L) and HL (C mol/L) mixed according to titrimetric mode (pH titration). A new derivation of the Michałowski formula 1 2 0 10 pK C C C    expressing this property is presented, and its applicability for determination of pK1 = – logK1 value is...

A novel and simple titrimetric method for determination of commonly used angiotensin-II-receptor antagonists (ARA-IIs) is developed and validated. The direct acid base titration of four ARA-IIs, namely eprosartan mesylate, irbesartan, telmisartan and valsartan, was carried out in the mixture of ethanol:water (1:1) as solvent using standardized sodium hydroxide aqueous solution as titrant, eithe...

Precipitation titrations are based upon reactions that yield ionic compounds of limited solubility. The most important precipitating reagent is silver nitrate. Titrimetric methods based upon silver nitrate are sometimes termed argentometric methods. Potassium chromate can serve as an end point indicator for the argentometric determination of chloride, bromide and cyanide ions by reacting with s...