Much attention during the early stages of basic and clinical research on dental implants has been focused on the bone (jaw)-to-titanium (implant) interface, because direct bone contact with the implant was thought to be a critical factor in implant therapeutics. However, since wide acceptance of the important concept of “osseointegration”, developed by Branemark et al. (1977) in the late 1960’s...

Introduction: According to anterior spine fusion intervertebral disc spacers made of titanium or cobalt-chromium alloys are of special interest. With regard to postoperative problems implant related artifacts can lead to a decreased MRI evaluation. The focus of this study was to compare the respective implant artifact range dependend on different MRI sequences. To simplify artifact evaluation w...

The aim of this study was to examine the influence of collagen coating on titanium on the initial attachment of human gingival fibroblasts for the development of the implant with periimplant soft tissue attachment. The morphological changes of cultured human gingival fibroblasts were investigated by scanning electron microcopy (SEM). Four different surfaces, i.e. non-coated mirror-polished tita...

The purpose of this study was to examine the dose enhancement at bone-implant interfaces from scattered radiation during simulated head and neck radiotherapy. Three cylindric implant systems with different compositions (pure titanium, titanium-aluminum-vanadium alloy, titanium coated with hydroxyapatite) and a high gold content transmandibular implant system (gold-copper-silver alloy) were stud...

Bone sections including either titanium or porous tantalum implant devices used for interbody spinal fusion were investigated with position-resolved small angle X-ray scattering (sSAXS). The samples were obtained from six-month-old pigs that had undergone surgery three months prior to sacrifice. The aim of the study was to explore the possibility of using sSAXS to obtain information about thick...

PURPOSE To evaluate clinical safety and effectiveness of a novel calcium-incorporated titanium implant (Xpeed, MegaGen Implant Co. Limited, Gyeongbuk, South Korea). MATERIALS AND METHODS Sixty patients were randomised to receive either 1 to 6 calcium-incorporated or control titanium implants in the maxilla according to a parallel group design at 2 different centres. Implants were submerged an...

Titanium implants are widely used in dental clinics and orthopaedic surgery. However, bone formation surrounding the implant is relatively slow after inserting the implant. The current study assessed the effects of bone marrow stromal cells (BMSCs) with forced expression of special AT-rich sequence-binding protein 2 (SATB2) on the osseointegration of titanium implants. To determine whether SATB...

Osseointegration is a major factor influencing the success of dental implants. To achieve rapid and strong durable osseoin-tegration, biomaterial researchers have investigated various surface treatment methods for titanium dental implants. Current dental implant research has studied the interaction between bone and implant surface in order to understand the osseointegration process. This specia...

Previous studies to compare the influence of surface characteristics of dental implants on cell behavior have used model systems to simulate the implant surface. In this study, bone cell interactions with smooth titanium, titanium dioxide-blasted, titanium plasma-sprayed, and hydroxyapatite plasma-sprayed implants, as manufactured for clinical use, were compared. Implants were exposed to neonat...

The implant used in spinal fusion procedures is an essential component to achieving successful arthrodesis. At the cellular level, the implant impacts healing and fusion through a series of steps: first, mesenchymal stem cells (MSCs) need to adhere and proliferate to cover the implant; second, the MSCs must differentiate into osteoblasts; third, the osteoid matrix produced by the osteoblasts ne...