BACKGROUND Most methods for monitoring glucose level require an external energy source which may limit their application, particularly in vivo test. Bioluminescence technique offers an alternative way to provide emission light without external energy source by using bioluminescent proteins found from firefly or marine vertebrates and invertebrates. For quick and non-invasive detection of glucos...

Colloidal quantum dots (QDs) are an emerging class of new materials due to their unique physical properties. In particular, colloidal QD based light emitting diodes (QDLEDs) have been extensively studied and developed for the next generation displays and solid-state lighting. Among a number of approaches to improve performance of the QDLEDs, the most practical one is optimization of charge tran...

Context Cadmium (Cd) toxicity and zinc (Zn) deficiency are of major concerns for crop growth quality. Moreover, their interactive effects exert some controversial reports. Aims The oxide nanoparticles (ZnO NPs) Cd on growth, physiology, metal distribution in mung beans (Vigna radiata L.) was investigated. Methods Seven-day-old seedlings were treated with Zn (0, 1, 2, 4, 8, 16 32 μM) 0.5, 1 14 d...

Herein, a novel and ultrasensitive label-free electrochemical immunosensor was proposed for quantitative detection of human Immunoglobulin G (IgG). The amino functionalized magnetic graphenes nanocomposites (NH2-GS-Fe3O4) were prepared to bond gold and silver core-shell nanoparticles (Au@Ag NPs) by constructing stable Au-N and Ag-N bond between Au@Ag NPs and -NH2. Subsequently, the Au@Ag/GS-Fe3...

Monitoring water quality has become a goal to prevent issues related human health and environmental conditions. In this sense, the concentration of metal ions in sources is screened, as these are considered persistent contaminants. work, we describe implementation customized graphite electrodes decorated with two types Hg nanoparticles (Hg-NPs), optimized toward electrochemical detection Cd, Pb...

Multiple applications of nanotechnology, especially those involving highly fluorescent nanoparticles (NPs) or quantum dots (QDs) have stimulated the research to develop simple, rapid and environmentally friendly protocols for synthesizing NPs exhibiting novel properties and increased biocompatibility. In this study, a simple protocol for the chemical synthesis of glutathione (GSH)-capped CdTe Q...

PURPOSE The aim of the study was to load a model antigen, tetanus toxoid (TT), in poly-ε-caprolactone nanoparticles (PCL NPs) of two size ranges, ie, mean 61.2 nm (small) and 467.6 nm (large), and study its effect on macrophage polarization as well as antigen presentation in human monocyte-derived macrophages in vitro, along with humoral and cell-mediated immune (CMI) response generated in Swis...

The objective of this research article is to report the synthesis and evaluation of novel pentablock copolymers for controlled delivery of macromolecules in the treatment of posterior segment diseases. Novel biodegradable PB copolymers were synthesized by sequential ring-opening polymerization. Various ratios and molecular weights of each block (polyglycolic acid, polyethylene glycol, polylacti...

The objective of this project was to develop a new approach to 3-D metamaterials. A key step was developing materials with large optical activity. A unique combination of "bottom up" and "top down" approaches to produce nanostructures was successfully applied. Multiscale modeling was used to design chiral polymers. A series of chiral polymers, based on thiophene, fluorene, and fluorene-quinoxal...

We describe a safe and highly effective non-viral vector system based on β-cyclodextrin (β-CD)-modified dendrimer-entrapped gold nanoparticles (Au DENPs) for improved delivery small interfering RNA (siRNA) to glioblastoma cells. In our approach, we utilized amine-terminated generation 5 poly(amidoamine) dendrimers partially grafted with β-CD as a nanoreactor to entrap Au NPs. The acquired β-CD-...