Macrophages are the first line of defense and constitute important participants in the bi-directional interaction between innate and specific immunity. Macrophages are in a quiescent form and are activated when given a stimulus. In the present study, we have used Tinospora cordifolia, commonly known as Guduchi, to see its effect on macrophage activation. The direct drug treatment to J774A cells...

Since the beginning of human civilization, medicinal plants have been used by mankind for its therapeutic value. Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs have been isolated from natural sources. Traditional medicine has remained as the most affordable and easily accessible source of treatment in the primary healthcare system of...

Polysaccharide from Tinospora cordifolia was isolated, purified, hydrolysed, trimethylsilylated and then subjected to GC-MC studies. The polysaccharide composition was estimated as follows: glucose 98.0%, arabinose 0.5%, rhamnose 0.2%, xylose 0.8%, mannose 0.2% and galactose 0.3%.

The details of isolation and spectral analysis of the protoberberine alkaloids, tetrahydropalmatin and jatrorrhizine, reported for the first time to occur in the roots of Tinospora cordifolia by the authors, are described.

Physio-chemical analysis of ash of Quercus infectoria, Cassia fistula, Tinospora cordifolia, Butea monosperma and Cedrela toona trees parts were carried out for present study. Atomic Absorption Spectroscopy (AAS) was used for quantitative estimation while chemical methods applied for qualitative estimation of minerals in plants ash. It is found that C. fistula, T. cordifolia, Q. infectoria and ...

Seed oils of Passiflora edulis, Jatropa curucas, Tinospora cordifolia, Sesbania grandiflora and Sapindus laurifolia were investigated for their antihelmintic property against Pheritima pasthuma. Three concentrations (10, 50 and 100 mg/ml) of each oil were studied in the bioassay, which involved the determination of time of paralysis and time of death of the worm. Sesbania grandiflora showed the...

18 BACKGROUND: The current practice of ingesting phytochemicals to support the immune 19 system or to fight infections is based on centuries-old tradition. Macrophages are involved at all 20 stages of the immune response. The present study focuses on immunostimulant properties of 21 Tinospora cordifolia in circulating macrophages of CCl4 (0.5 ml/kg body weight) intoxicated 22 male albino mice. ...

Many plants are claimed to possess antidiabetic and antioxidant activity. In practice, it is being increasingly recognized to be an alternative approach to modern medicine. This study assess the antioxidant capacity of Tinospora cordifolia stem methanol extract in daily oral administration of 500 mg/kg of body weight for 40 days in alloxan induced diabetic rats. The erythrocytes membrane lipid ...

n-octacosanol is an normolipidemic aliphatic primary alcohol obtained from the plant Tinospora cordifolia Miers. In the present study, the plant stems were collected from five accessions namely Anniyalam, Chennai, Hassan, Vishakhapatnam and Bangalore between June and August. Later a simple HPTLC method has been established for determination of n-octacosanol in methanolic extracts of all these g...

The present study deals with the antimicrobial activity and phytochemical screening of the two medicinal plants, Tinospora cordifolia and Euphorbia hirta those are commonly available in India. Results of antimicrobial activity revealed that these medicinal plant extracts were very effective against Serratia marcescens, E. coli, Streptococcus thermophilus, Fusarium oxysporium, Aspergillus niger ...