In this paper, the time and norm optimal control problems of controlled heat equations with a weight function are considered. For the time optimal problems, we study the following two cases: one is for equations with multi-domain control under null controllability, and the other is for equations under approximate null controllability. We prove the solvability, and obtain the bang-bang principle...

This paper presents an efficient optimization procedure to find the optimal shapes of double curvature  arch  dams  considering  fluid–structure  interaction  subject  to  earthquake  loading. The optimization is carried out using a combination of the magnetic charged system search, big bang-big crunch algorithm and artificial neural network methods. Performing the finite element  analysis  dur...

We use conductance based neuron models, and the mathematical modeling of optogenetics to define controlled neuron models and we address the minimal time control of these affine systems for the first spike from equilibrium. We apply tools of geometric optimal control theory to study singular extremals, and we implement a direct method to compute optimal controls. When the system is too large to ...

We consider a general mathematical model for cancer chemotherapy as optimal control problem for a bilinear system and give necessary and sufficient conditions for strong local optimality of bang-bang controls. These results apply to a 3-compartment model which besides a killing agent also includes a recruiting agent, i.e. a drug which acts on the residuum of dormant cells in the cell cycle. For...

In the paper, we consider ODE driven optimal control problems with bang-bang type extremals. The specific nature of bang-bang controls causes some difficulties in optimality and stability analysis. Usual convexity arguments like (strong) Legendre-Clebsch condition fail to hold, and the control discontinuity has to be taken into account. In recent years, substantial results on secondorder optima...

In this paper, we study two subjects on internally controlled heat equations with time varying potentials: the attainable subspaces and the bang-bang property for some time optimal control problems. We present some equivalent characterizations on the attainable subspaces, and provide a sufficient conditions to ensure the bang-bang property. Both the above-mentioned characterizations and the suf...

In this paper, we study optimal control problems associated with a scalar hyperbolic conservation law modeling the development of ovarian follicles. Changes in the age and maturity of follicular cells are described by a 2D conservation law, where the control terms act on the velocities. The control problem consists in optimizing the follicular cell resources so that the follicular maturity reac...

In this paper we consider the minimum time population transfer problem for the z-component of the spin of a (spin 1/2) particle driven by a magnetic field, controlled along the x axis, with bounded amplitude. On the Bloch sphere (i.e. after a suitable Hopf projection), this problem can be attacked with techniques of optimal syntheses on 2-D manifolds. Let (−E,E) be the two energy levels, and |Ω...